=Narcotics.= Next must be noted those alimentary matters which are hurtful by reason of narcotic constituents. At the head of this list may be placed the lolium temulentum or intoxicating ryegrass. like the vicia sativa or cicera, the seeds of this are always poisonous, hence its significant name. Then the other ryegrasses, perennial and annual (Italian), though perfectly safe in ordinary circumstances, develop at the period of ripening a narcotic principle, which produces cerebral congestion or inflammation in whole stables of horses at a time. The lolium temulentum is poisonous to man and animals alike. Baillet and Filhol obtained from the seeds an etherial extract containing a bland oil to the amount of two fifths and a yellow extract to the extent of three-fifths. The amount of this extract derived from three ounces of the seeds often developed the most violent symptoms in the dog, while that furnished by six pounds of the seeds proved fatal to the horse. Pigs and cattle seemed to be unaffected by the agent when given by the mouth. Sheep suffered more but required large doses. Ducks and chickens were practically immune, being affected only by very large doses. Rabbits were not poisoned by the yellow etherial extract, but succumbed to a watery extract. Brydon found that lambs suffered extensively from eating the heads of the ryegrass. Lupins on certain lands produces an icteric disorder accompanied by cerebral symptoms but the result is not the same under all conditions and it has been suspected that the symptoms were caused by cryptogams and their products. The same remark applies to the brain symptoms sometimes produced by trefoil, equisetum and other plants. A great number of =narcotic= and =narcotico-acrid= plants produce nervous symptoms indicating cerebral congestion or inflammation such as ranunculus, wild poppy, digitalis, fennel, œnanthe crocata, hellebore, veratrum, conium, yew, tobacco, box, aconite, cicuta virosa, even buckwheat at the time of flowering, vetch and flax.