The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
The particular way in which nerve-medicines affect different parts of
the nervous system might perhaps be explained by supposing minute
chemical differences in the composition of the atoms of which those
parts are constructed, sufficient to alter their relations to the atoms
of certain remedies. If we adopt the Atomic theory, we must perceive
that no two chemical bodies can be precisely alike in the shapes of
their particles. This various dissimilarity might throw some light upon
the many shades of distinction between the operations of Neurotic
medicines on different parts. Thus, as a general rule, both Morphia and
Atropia are paralyzers of motor nerves. But they do not act alike on the
Ciliary nerves by which the motions of the Iris are controlled. We may
suppose that there is a certain chemical peculiarity in the particles of
these nerves, by which they are enabled to coincide with the atoms of
Atropia, and are thus blunted and paralyzed by them; but are, on the
contrary, stimulated and excited by the atoms of Morphia, which have the
contrary action, because unable, on account of their relative shape, to
dove-tail with these atoms.
This idea is, as I have said, purely conjectural and fictitious, and is
indeed likely to remain so; for the thing is not by its nature
susceptible of proof, nor is it even possible to inquire into it. And I
have only thought it worth while to explain it at length because it is
desirable that every statement which is made, however improbable and
unworthy of credence it may seem, should at least be placed in as clear
a light as possible.
The action of a Neurotic is readily distinguished from that of Hæmatic
medicines by the fact of its exerting a rapid and well marked influence
of some kind on the nervous system. As it is impossible that the
medicines contained in this class should remain in the blood, they
therefore pass out of the blood through the glands, and in so doing
generally act as Eliminatives. This, their secondary action, will be
subsequently considered. It is generally of less importance than their
action on nerve; with the exception of some which, as volatile oils and
resins, exert a very feeble Neurotic action, but are comparatively
powerful as Eliminatives. In this case the secondary action becomes the
more important of the two.
Public-domain text, read in full here on John Shaqi.
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