The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
Phosphorus is a Stimulant. In small doses it quickens the pulse. It
somewhat heightens the mental activity. It is said also to have an
aphrodisiac operation, due to its powers as a cerebral excitor. Volatile
oils possess a certain influence over the functions of the brain, as
well as those of the organic nerves. Cajeput oil has been used in
Hysteria; employed to control various spasmodic movements; and
administered in Typhoid fevers and Asiatic Cholera, to communicate
nervous power. The fetid gum resins are well known as Antispasmodics.
The spasms which these medicines relieve are due to a fault in the
nervous polarity, commencing generally in the brain or
nerve-centres,--and are more or less subdued by general stimulators of
the nervous functions. Copaiba, an oleo-resin, may cause a general
febrile condition, accompanied with headache,--when given in large
doses.
So obvious is the cerebral power of some volatile oils, that Turpentine,
in large doses, has been known to produce inebriation. It is not
generally used for its Neurotic powers, but as a Purgative or a
Diuretic; or else it might have been classed among Inebriant Narcotics.
I have enumerated it above among volatile oils. It may be regarded as
transitional between true Stimulants and Narcotics.
Ergot of Rye is another medicine which has a double action. It is used
as a Special Stimulant to the Uterus; but it is also a Narcotic to the
brain.
Most General Stimulants are without any marked influence on the mind;
but stimulate the organic and merely animal function of the brain, and
of the Sympathetic nerve throughout the system.
Concluding that General Stimulants have all more or less the power of
exalting nervous force in general, we have still to consider some other
questions relating to their action.
It is maintained by some that Stimulants have simply the power of
calling forth the nervous force which already exists in the system, and
that they cannot create any more in addition to this. But if this were
the case, then the reaction, or subsequent failure of nervous power,
ought to be exactly equivalent to the first temporary increase of that
power; assuming this increase to have been simply abstracted from the
natural resources. But we do not find it to be so. The reaction from the
effect of a Stimulant is always very slight, and often quite
imperceptible.
And there seems to be no _à priori_ reason why we should not actually
cause nervous force to be generated. We know that a galvanic current, or
even a mechanical cause, may induce it to be suddenly and powerfully
manifested. I believe that a Stimulant is able actually to produce
nervous action; perhaps by an irritative operation upon nerve-fibre. So
by continually repeating the dose of a Stimulant, as Ammonia or Brandy,
it is possible to maintain the circulation and nervous energy at a
certain level, without the occurrence of any reaction for a considerable
period.
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