The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
Opium, which is the chief and only important medicine of this order, may
be considered as the type of Narcotics. It causes in the first place a
slight quickening of the pulse, and some excitement of the mental
faculties. It is named from its peculiar secondary action on the latter.
It produces drowsiness and sleep.
We have seen that the term _intellectual function_ must be understood to
include not only the mind itself, but also the powers of volition and
sensation, by which the mind is connected with the body,--and the five
senses, by which it is enabled to appreciate the external world.
Inebriants affect these three in about the same ratio. Ordinarily they
impair the mind, and derange the functions with which it is connected;
but they do not quite extinguish either volition, sensation, or the
special senses. Soporifics differ from this action in two ways. In sleep
the mind may remain active; but it is left alone, dreaming, and
uncontrolled by physical ties. For the functions of volition and
sensation, and the special senses of Sight, Hearing, Smell, and Taste,
are entirely suspended in perfect sleep. So that while Inebriants affect
similarly both the mind and the natural functions with which it is
connected, Soporifics may leave the first untouched, but they entirely
subdue the latter. The condition of sleep differs also in another
important particular from the state of inebriation,--as well as from
delirium, which we shall have presently to consider. Sleep is liable to
be suddenly interrupted or suspended by comparatively slight causes, as
a physical shock, or a forcible impression upon one of the senses which
are held in abeyance and subjection. Neither inebriation nor delirium
can be suddenly put an end to in this way.
Such appears to be the distinction between the operations of these two
orders of medicines.
Pain prevents sleep, because it enforces sensation. Thus a mere
Soporific, if effectual, would prove anodyne, and relieve pain.
But Opium has an important anodyne action, which is independent of its
power of producing sleep, for it may occur without the latter. It is by
far the best remedy for pain in the whole catalogue of medicines. It
also produces relaxation of the muscular system, and is thus a powerful
antispasmodic. In excessive dose it produces a marked sedative effect;
causing an imperceptible or irregular pulse, and very slow breathing,
with contraction of the pupil of the eye. It may kill by apn[oe]a;
_i.e._ by stopping the respiration.
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