The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
Antimony, Ipecacuanha, and Digitalis, have each of them a number of
different actions. The first has already been included among Catalytic
Hæmatics, as tending to counteract in the blood the process of
inflammation. But it possesses further a Neurotic power, by which it is
gifted indirectly with a more powerful control over acute inflammations
than could be exerted by any slow-acting blood-medicine. It is also
Eliminative. Passing out of the body through the glands of the skin, it
becomes a Diaphoretic. This may be its only action when it is given in
doses too small to act upon the nerves. It must not be confounded with
the diaphoresis which accompanies the condition of nausea, and which is
probably produced in another way. Ipecacuanha is in the first place a
Neurotic, of less power than Antimony; in the second place an
Eliminative, increasing expectoration, as well as Diaphoresis. Digitalis
too acts first upon the nervous system; then on the kidneys, being a
Diuretic.
But we are now concerned with the special Neurotic actions of this group
of medicines. They all exert an influence over the three functions of
respiration, circulation, and digestion. They affect the heart, lungs,
and stomach, parts which are supplied by the branches of the Vagus
nerve, as well as by the Sympathetic. Their action is not an external
action, for it is produced when they are introduced into the blood at
any part. Thus Tartar Emetic or Ipecacuanha, when injected in solution
into one of the veins, will cause vomiting. M. Magendie has found that
in the case of dogs they also produce Pneumonia. The mere inhalation of
the dust of Ipecacuanha has been found to act upon the lungs so as to
cause Bronchitis. These actions, as well as the various effects which
are found to follow the introduction of these medicines into the
stomach, can only be explained satisfactorily by supposing that they act
as Sedatives to the branches of the Vagus nerve, thereby deranging or
destroying the natural influence of that nerve in the direction and
regulation of the organs which it supplies. For we have already seen
that the action of a Sedative medicine is of such a nature as to derange
nervous force in some cases, and simply subdue it in others.
Public-domain text, read in full here on John Shaqi.
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