The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
This appears to be the reason why the Eliminatives which are volatile in
nature tend particularly to act on the two aeriform secretions,--_i.e._
on that of the air-cells of the lungs, and on the common cutaneous
transpiration. For though the glands of the mucous membrane of the
lungs secrete mucus, yet the chief object of the terminal portion of
that membrane is to absorb and secrete the gaseous matters of the blood.
The following are the chief volatile Expectorants, the odours of which
have been clearly detected in the breath of persons to whom they have
been administered:--Turpentine, Camphor, Alcohol, Ether, and the
volatile oils of Onions, Fennel, Asaf[oe]tida, Carraway, Cinnamon, and
Anise.
These medicines, and others like them, are thus excreted by the
air-cells or mucous glands of the pulmonary surface, and while thus
passing through they stimulate the latter to a right performance of
their function. When, as in the case of Bronchitis, the secretion of
mucus is increased in amount, or deteriorated into a purulent matter,
they may be of service by causing the healthy secretion to replace the
diseased one.
Expectorants are very uncertain agents. The reason of this is, that the
pulmonary glands are not naturally intended to act as emunctories, or
dischargers of morbid matters from the blood, and thus are less prone to
be excited by Eliminative medicines than other glands whose proper
office is one of general elimination. And yet we find that the effete
gases which should be excreted by the bowels are sometimes voided by the
lungs in case of aggravated dyspepsia, causing tainted breath. Just so
may other adventitious elements of the blood, as these volatile
medicines, be sometimes excreted by the pulmonary membrane. But they may
often pass off by the skin or by the urine, and would not then act upon
the lungs at all.
For the same reason that the lungs are not general emunctories, and
cannot be made use of to produce a wholesale evacuation from the blood,
Expectorants are of no use as general Antiphlogistics. In this they
differ from the four remaining groups of Eliminatives.
They are only employed in pulmonary disorders, where we desire to
influence the amount or character of the mucous secretion, when the
mucous membrane is inflamed or irritated. In old and chronic cases of
Bronchitis the stimulant volatile Expectorants are the most applicable.
Tartar Emetic and Ipecacuanha are appropriate in acute and inflammatory
cases, because they exert a nauseating and depressing action. They are
sometimes given in sufficient dose to act as Emetics; for the act of
vomiting mechanically assists the expulsion of mucus from the air-cells
and passages by causing straining and compression of the lungs.
ORD. III. CATHARTICS.
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