The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
In the treatment of constipated habits it is better to keep up a
constant and gentle action on the bowels than to give violent doses
occasionally. A condition of this sort may sometimes co-exist with
comparative health, and may then often be remedied by a slight
alteration in diet, and the prescription of such kinds of food as are
more relaxing in their nature than those hitherto taken. Dr. Hamilton,
in his work on Purgative Medicines, states that when they are given in
constipation he has found that they become more and more powerful, and
may be taken in smaller and smaller doses the longer they are continued.
This is probably the case with such as Castor-oil, Scammony, and Jalap,
which are simply cathartic in their action. But others, such as Rhubarb
and Aloes, contain a bitter and astringent matter along with the
purgative principle, and though they first act upon the bowels tend for
this reason in the second place to confine them. Thus while the former
are best in cases of constipation, the latter are preferable in
diarrh[oe]a, as they supply us then with the very action which we
require.
There are two ways, apparently opposite and inconsistent, of treating a
flux from the bowels. We may try to encourage it by Purgatives; or
attempt to suppress it by Astringents. Thus we may treat a common
diarrh[oe]a by Castor-oil, or by Sulphuric Acid. In dysentery we may
give Calomel, or Catechu. Even in Cholera some recommend Opium, while
others have employed Croton-oil. In the most obvious case, _i.e._ in
simple diarrh[oe]a, it is apparent that both plans are appropriate, but
at different periods of the disorder. The symptom depends upon the fact
of something being formed in the blood which ought to be excreted from
it. Probably it is an excess of that material which is ordinarily
excreted by the bowels. Its passage out by a natural effort causes at
first a simple increase of the usual evacuation. It is at this time that
we should give a Purgative, to favour the natural excretion, and thus,
if possible, to put an end to the disturbance. But sometimes it fails to
do so. The matters to be excreted are irritating, and such an
excitement may be caused in the glands by their passage out, that even
after this necessary secretion an inordinate and unnatural flux may be
maintained. When the symptom is thus inveterate, and refuses to yield to
a brisk Cathartic, it is advisable to resort to Astringents, in order to
put a speedy stop to the too copious secretion. To do this in the first
instance would have been wrong, except in special instances,--as in the
diarrh[oe]a which is the forerunner of cholera, when Astringents should
be used from the first.
Public-domain text, read in full here on John Shaqi.
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