The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economyHeadland, Frederick William
Science
The Action of Medicines in the System: Or, on the mode in which therapeutic agents introduced into the stomach produce their peculiar effects on the animal economy
Headland, Frederick William
Therapeutics
The nitrogenous Aliments are needed particularly to supply the growth
and waste of the muscular and nervous tissues, which both contain
Nitrogen; as also do all the parts of the body, excepting Fat. This
waste is continually going on. It depends upon the fact that, after
having lasted a certain time, the particles of all these tissues are
gradually displaced, oxidized, and conveyed away out of the blood into
the urine and other secretions. In the urine these waste matters are
found as Urea, Uric acid, and Kreatine.
The starchy and saccharine parts of the food are destined to pass
through a series of changes, which ends also in their being burnt and
oxidized, maintaining the animal heat, and forming Carbonic acid. Starch
passes first into grape-sugar, by taking into itself two atoms of water,
becoming C_{12}H_{12}O_{12}. The Ptyaline of Saliva, Pepsin of the
gastric juice, and some similar principle in the Pancreatic fluid, are
all capable of causing this first transformation. This sugar is more
soluble than Starch. When in the blood, it undergoes a further change,
the nature of which is not so clear. It is supposed to be into Lactic
acid (C_{6}H_{5}O_{5}, HO_{7}) whose equivalent number is just half that
of anhydrous grape-sugar, so that one atom of the latter may become two
of the former. This important compound was found by Berzelius, in 1807,
to exist constantly in the juice of muscle, as well as in the urine and
sweat. (_Annuaire_, 1848, p. 347.) Liebig at first controverted this,
but in 1847 he assented to the statement of Berzelius, which had already
been further confirmed by the experiments of M. Pelouze. Many modern
chemists, among whom may be mentioned Dr. Bence Jones,[32] consider that
Lactic acid, or some compound nearly resembling it, is formed at this
step of the process of changes connected with the function of
respiration. The acid next combines with free Soda, existing in the
blood; and this salt is oxidized into Carbonate of Soda and water, just
as a Tartrate or a Citrate might be. (_Vide_ page 127.) This has been
ascertained by Magnus and Dumas.
Fatty matters are used in the production and renovation of the adipose
tissues; and may also, like the last, be burnt and oxidized to support
the animal heat.
As a general rule, the diet of a man in health should contain a due
proportion of all four kinds of food; for each one of them is essential,
and has its proper function in the system. The albuminous material
cannot be dispensed with; and is also the only food which will suffice
by itself to sustain life. The mode in which it can adapt itself to
perform the office of the other varieties of food was ill understood,
until explained by the researches of M. Bernard.
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