The cause, nature, and treatment of this disease is so little understood among medical men, and such an alarming mortality attends their practice, that many of the inhabitants of the west and south-west depend entirely on their domestic remedies. "It is in that country emphatically one of the _opprobria medicorum_." Nor are the mineralites any more successful in the treatment of other diseases incidental to the Great West. Their Peruvian bark, _quinine_, and calomel, immense quantities of which are used without any definite knowledge of their _modus operandi_, fail in a great majority of cases. If they were only to substitute powdered charcoal and sulphur for calomel, both in view of prevention and cure, aided by good nursing, then the mortality would be materially diminished. The success attending the treatment of upwards of sixty cases of yellow fever, by Mrs. Shall, the proprietress of the City Hotel, New Orleans, only one of which proved fatal, is attributed to good nursing. She knew nothing of blood-letting, calomelizing, narcotizing. The same success attended the practice of Dr. A. Hunn, of Kentucky, in the treatment of typhus fever, (which resembles milk sickness,) who cured every case by plunging his patients immediately into a hot bath. "The whole indication of cure in this disease is to bring on reaction, to recall the poison which is mixed with the blood and thrown to the centre, which can only be done by inducing a copious perspiration in the most prompt and energetic manner. If I mistake not, where sweating was produced in this complaint, recovery invariably followed, while bleeding, mercury, &c., only aggravated it." From such facts as these, as well as from numerous others, we may learn, that disease is not under the control of the boasted science of medicine, as practised by our allopathic brethren. Many millions of animals, as well as members of the human family, have died from a misapplication of medicine, and officious meddling. The destruction that in former years attended milk sickness may be learned from the fact, that in the western settlements, its prevalence often served as a cause to disband a community, and compel the inhabitants to seek a location which enjoyed immunity from its occurrence. The legislatures of several of the Western States have offered rewards for the discovery of the origin of the milk sickness. No one that we know of has ever yet claimed the reward. In view of the great lack of information on this subject, we freely contribute our mite, which may serve, in some degree, to dispel the impenetrable mystery by which it is surrounded. We shall first show that it is not produced by the atmosphere alone, which by some is supposed to be the cause. "It is often found to occupy an isolated spot, comprehending an area of one hundred acres, whilst for a considerable distance around it is not produced."