any time the cold became excessive, we had recourse to our dram, which ensured us warmth and comfort for the next twelve or fourteen miles, without, on any occasion producing the slightest feeling of intoxication. Nor had the spirits which we took any bad effects either upon the other passengers or myself. On the contrary, we were all, so far as I could learn, much the better of it; nor can there be a doubt, that without spirits, or some other stimulating liquor, the consequences of such severe weather would have been highly prejudicial to most of us. Some persons deny that spirits possess the property of enabling the body to resist cold, but, in the face of such evidence, I can never agree with them. That, under these circumstances, they steel the system, at least for a considerable time, against the effects of a low temperature, I am perfectly satisfied. Analogy is in favour of this assertion, and the experience of every man must prove its accuracy. At the same time, I do not mean to deny that wine or ale might have done the same thing equally well, and perhaps with less risk of ulterior consequences. We had no opportunity of trying their efficacy in these respects, and were compelled, in self-defence, to have recourse to what, in common cases ought to be shunned, _viz._, raw spirits. The case was an extreme one, and required an extreme remedy; such, however, as I would advise no one to have recourse to without a similar plea of strong necessity to go upon. It follows, then, that if spirits are often perverted to the worst purposes, and capable of producing the greatest calamities, they are also, on particular occasions, of unquestionable benefit. In many affections, both they and wine are of more use than any medicine the physician can administer. Wine is indicated in various diseases of debility. Whenever there is a deficiency of the vital powers, as in the low stages of typhus fever, in gangrene, putrid sore throat, and, generally speaking, whenever weakness, unaccompanied by acute inflammation, prevails, it is capable of rendering the most important services. Used in moderation, it enables the system to resist the attack of malignant and intermittent fevers. It is a promoter of digestion, but sometimes produces acidity, in which case, spirits are preferable. To assist the digestive process in weak stomachs, I sometimes prescribe a tumbler of negus or toddy to be taken after dinner, especially if the person be of a studious habit, or otherwise employed in a sedentary occupation. Such individuals are often benefited by the stimulus communicated to the frame by these cordials. In diarrhœa, dysentery, cholera, cramps, tremors, and many other diseases, both spirits and wine often tell with admirable effect, while they are contra-indicated in all inflammatory affections. Malt liquors also, when used in moderation, are often beneficial. Though the drunkenness produced by their excessive