The disease generally comes on with lassitude, loss of appetite, and frequent exacerbations of cold. The pulse is weak and quick, and the body covered with a chilly moisture. The countenance is pale, there are usually tremors of the limbs, anxiety, and a total disrelish for the common amusements of life. Then succeed retching, vomiting, and much oppression at the pit of the stomach, with sometimes slimy stools. When the person sleeps, which is but seldom, he frequently starts in the utmost terror, having his imagination haunted by frightful dreams. To the first coldness, glows of heat succeed, and the slightest renewed agitation of body or mind, sends out a profuse perspiration. The tongue is dry and furred. Every object appears unnatural and hideous. There is a constant dread of being haunted by spectres. Black or luminous bodies seem to float before the person: he conceives that vermin and all sorts of impure things are crawling upon him, and is constantly endeavouring to pick them off. His ideas are wholly confined to himself and his own affairs, of which he entertains the most disordered notions. He imagines that he is away from home, forgets those who are around him, frequently abuses his attendants, and is irritated beyond measure by the slightest contradiction. Calculations, buildings, and other fantastic schemes often occupy his mind; and a belief that every person is confederated to ruin him, is commonly entertained. Towards morning there is often much sickness and sometimes vomiting. This state generally lasts from four to ten days, and goes off after a refreshing sleep; but sometimes either from the original violence of the disease, or from improper treatment, it proves fatal. Such, in nine cases out of ten, is the character of delirium tremens. Sometimes, however, the symptoms vary, and instead of a weak there is a full pulse; instead of the face being pallid, it is flushed and the eyes fiery; instead of a cold clammy skin, the surface is hot and dry. This state only occurs in vigorous plethoric subjects. An habitually sober man who has thoughtlessly rushed into a debauch, is more likely to be attacked in this mariner than a professed drunkard. Indeed, I never met with an instance of the latter having this modification of the disease. When the patient perishes from delirium tremens he is generally carried off in convulsions. There is another termination which the disease sometimes assumes: it may run into madness or confirmed idiotism. Indeed, when it continues much beyond the time mentioned, there is danger of the mind becoming permanently alienated. Subsultus, low delirium, very cold skin, short disturbed sleep, contracted pupil, strabismus, rapid intermittent pulse, and frequent vomiting, are indications of great danger. When the patient is affected with subsultus from which he recovers in terror, the danger is extreme.