Of the matter of melancholy, there is much question betwixt Avicen and Galen, as you may read in [1057]Cardan's Contradictions, [1058]Valesius' Controversies, Montanus, Prosper Calenus, Capivaccius, [1059]Bright, [1060]Ficinus, that have written either whole tracts, or copiously of it, in their several treatises of this subject. [1061]What this humour is, or whence it proceeds, how it is engendered in the body, neither Galen, nor any old writer hath sufficiently discussed, as Jacchinus thinks: the Neoterics cannot agree. Montanus, in his Consultations, holds melancholy to be material or immaterial: and so doth Arculanus: the material is one of the four humours before mentioned, and natural. The immaterial or adventitious, acquisite, redundant, unnatural, artificial; which [1062] Hercules de Saxonia will have reside in the spirits alone, and to proceed from a hot, cold, dry, moist distemperature, which, without matter, alter the brain and functions of it. Paracelsus wholly rejects and derides this division of four humours and complexions, but our Galenists generally approve of it, subscribing to this opinion of Montanus. This material melancholy is either simple or mixed; offending in quantity or quality, varying according to his place, where it settleth, as brain, spleen, mesaraic veins, heart, womb, and stomach; or differing according to the mixture of those natural humours amongst themselves, or four unnatural adust humours, as they are diversely tempered and mingled. If natural melancholy abound in the body, which is cold and dry, so that it be more [1063]than the body is well able to bear, it must needs be distempered, saith Faventius, and diseased; and so the other, if it be depraved, whether it arise from that other melancholy of choler adust, or from blood, produceth the like effects, and is, as Montaltus contends, if it come by adustion of humours, most part hot and dry. Some difference I find, whether this melancholy matter may be engendered of all four humours, about the colour and temper of it. Galen holds it may be engendered of three alone, excluding phlegm, or pituita, whose true assertion [1064]Valesius and Menardus stiffly maintain, and so doth [1065]Fuschius, Montaltus, [1066] Montanus. How (say they) can white become black? But Hercules de Saxonia, lib. post. de mela. c. 8, and [1067]Cardan are of the opposite part (it may be engendered of phlegm, etsi raro contingat, though it seldom come to pass), so is [1068]Guianerius and Laurentius, c. 1. with Melanct. in his book de Anima, and Chap. of Humours; he calls it asininam, dull, swinish melancholy, and saith that he was an eyewitness of it: so is [1069]Wecker. From melancholy adust ariseth one kind; from choler another, which is most brutish; another from phlegm, which is dull; and the last from blood, which is best. Of these some are cold and dry, others hot and dry, [1070]varying according to their mixtures, as they are intended, and remitted. And indeed as Rodericus a Fons.