accompanied by his wife; but, notwithstanding the strait-waistcoat, he left no means untried to kill himself. On arriving at Paris, and being again confined, he became perfectly reasonable, and made no attempt to destroy himself during the six weeks that his second confinement lasted. There was reason to believe his cure complete. If he was asked why he did not overcome his terrible impressions at his own house as he did at Paris, he answered in an evasive manner, affirming that this time the trial had been long enough, that he was cured, and that he insisted upon returning home. “Deprived of my wife and son,” said he, “I am the most unhappy of men, and I cannot live.” “But if you are so unhappy here,” said Esquirol to him one day, “why do you not try to destroy yourself, as it is very easy to do so?” “I know not,” he replied; “but I am cured, and I wish to live.” This patient enjoyed the greatest liberty, and although no apparent precaution was taken to prevent his destroying himself, he never made the least attempt. He afterwards ceased to talk unreasonably; but Esquirol was never able to obtain an avowal of the motives which induced him to commit suicide at his own house, whilst he thought no more of it as soon as he came amongst strangers. On returning to his home for the fourth time, although he was able to transact important business, the same phenomena returned with equal violence. M.——, twenty-seven years old, after experiencing some reverses of fortune, became maniacal, with a tendency to commit suicide. The elevated situation of the room which he inhabited, the position of the staircase, the reiterated visits of his friends, “who came to contemplate his misfortunes,” and the despair of his wife, were so many circumstances which induced him to terminate his existence; and although he avowed that he had no motive for so doing, and that he was ashamed, and considered himself criminal for having attempted it, he left no means untried for more than a month to effect that end. When he was taken away from his home, and lodged in a ground-floor which led into a garden, the idea no longer harassed him. “It would be of no use,” he said; “I could never kill myself here; every precaution is taken to prevent me.”