_The most convenient opportunity to introduce them to the Stomach_--is early in the Morning, when it is unoccupied,--and has no particular business to attend to, _i. e._ at least half an hour before Breakfast. _Physic_ should never interrupt the Stomach, when it is engaged in digesting _Food_--perhaps the best time to take it, is when you awake out of your first Sleep--or as soon as you awake in the morning. Moreover, such is the increased sensibility of some Stomachs at that time, that half the quantity of Medicine will suffice. From _two to four Persuaders_ will generally produce one additional motion within twelve hours. They may be taken at any time--by the most DELICATE FEMALES, whose Constitutions are so often distressed by Constipation[106], and destroyed by the drastic purgatives they take to relieve it. See also page 224. Their agreeable flavour recommends them as the most convenient aperient for CHILDREN, whose indispositions most frequently arise from obstructions in the Bowels;--it is not always a very easy task to prevail upon a spoiled Child to take Physic;--therefore--we have made our Pill to taste exactly like Gingerbread. For INFANTS, too young to swallow a Pill, pound it, and mix it with Currant Jelly, Honey, or Treacle. ON THE FIRST ATTACK OF DISEASE--it may generally be disarmed by discharging the contents of the Bowels:--IN EVERY DISORDER[107] the main point is carefully to watch, and constantly to keep up the activity of the Alimentary Canal--for want of due attention to this, MILLIONS (especially of _Children_) HAVE DIED OF MEDICABLE DISORDERS!! FOR BILIOUS OR LIVER[108] COMPLAINTS, (which are now the fashionable names for all those deranged sensations of the Abdominal Viscera--which as often arise from the want, as from the excess of Bile--and perhaps most frequently from _Indigestion_)--and for expelling WORMS[109], for which it is the fashion to administer _Mercury_[110] (which, because it is the only remedy for one Disease, people suppose must be a _panacea_ for every disorder) and other drastic mineral medicines, which are awfully uncertain both in their strength and in their operation. If, instead of two or three times a week tormenting your Bowels with _Corrosive Cathartics_,--_Hydragogues_,--_Phlegmagogues_, &c., you take one or two gentle PERSUADERS, twice or thrice a day;--they will excite a gradual and regularly increased action of the Viscera--restore the tone of the Alimentary tube--and speedily and effectually cure the disorder, without injuring the Constitution.