Not long after this, while Dr. Trudeau was lying ill and depressed in New York City, there came from Saranac Lake the news that during the night his house, cultures, guinea-pigs--everything--had been destroyed by fire! It was the last straw. The sick man was in despair; but his indomitable spirit came to the rescue again, and a letter signed by William Osler helped him to accept fresh battle. “I am sorry, Trudeau,” wrote Dr. Osler, “to hear of your misfortune, but take my word for it, there is nothing like a fire to make a man do the phœnix trick!” The phœnix rose from its ashes, with the financial help of George C. Cooper, of New York. Near the ruins of Dr. Trudeau’s first house was built the first and best-equipped laboratory in the United States for the study of tuberculosis. Here Trudeau labored for years, searching, as he often said, “in the haystack for the needle that we know is there.” Here his followers still work at all hours in immunizing experiments and in the testing of proposed specific remedies for the cure of tuberculosis. Here many a “patent remedy” of the “cure-consumption” order has met its Nemesis. Here, years before either Friedmann or Piorkowski tried to commercialize his so-called remedies through the press of two continents, the turtle-germ of both was weighed in the scientific balance and discarded as useless. It is not a breach of confidence now to reveal the fact that an article entitled “Has Dr. Friedmann found a Cure for Tuberculosis?” which appeared on two pages of the New York _Times_ on the very morning when the Berlin physician landed in New York, came from the Saranac Laboratory and was the work of several scientific brains, with Dr. Trudeau’s as the master-mind on the subject. That article changed overnight the opinions of many in the medical world regarding the merits of Friedmann’s “specific.” Dr. Trudeau had examined the turtle organism years before, and had labeled it, not only harmless, but quite useless, as an immunizing agent in human tuberculosis. To go back to the early days of sanitarium work, the success Trudeau achieved by his open-air and rest methods attracted great attention. The sanitarium grew swiftly. Other states of the Union built institutions of somewhat similar design and for similar treatment. To-day, as already remarked, there must be fully five hundred sanitaria for this method of treatment of pulmonary tuberculosis throughout the United States and Canada. The valley of the Saranac itself, with the adjacent Adirondack region, contains several private and state sanitaria that owe their inception, directly or indirectly, to the influence of Trudeau.