SECOND.--The kidneys and liver are the sewers of the system, and unless they are kept in perfect working order no amount of public sanitation can prevent epidemics raging among the people. The prudent man, _in the winter and spring_, will fortify the system against an such possibility. Dr. Koch, the celebrated German scientist and physician, says, for instance, that cholera will have but little effect among those who keep the digestive organs and the kidneys and liver in healthful operation. Warner's SAFE Remedies are the best scientific curatives and preventives, and should be used _now_ as a safeguard against any future scourge. SCIENTIFIC SPECIFICS. THIRD.--_We do not cure every known disease from one bottle_, for Warner's SAFE Remedies number seven scientific specifics, which have been put upon the market, only in obedience to strong public demand. RECOGNIZED STANDARDS. FOURTH.--Warner's SAFE Remedies, spite of all opposition, have won the favor of the profession as well as the masses, and are recognized as the leading standard medical preparations. STRONG GUARANTEES. FIFTH.--After six years of unequaled experience, we can give these unqualified guarantees: GUARANTEE I.--_Pure and Harmless._ That Warner's SAFE Remedies are pure and harmless. GUARANTEE II.--_Testimonials Genuine._ That the Testimonials used by us, so far as we know, are bona fide, with a forfeit of $5,000 for proof to the contrary. GUARANTEE III.--_Curative Effects Permanent._ That Warner's SAFE Remedies are not _merely temporary, but permanent_, in their curative effects and will sustain every claim, if used _sufficiently_ and as directed. PROOFS OF PERMANENCY. SIXTH.--Special inquiry among hundreds of our oldest patients results in unequivocal testimony that the cures wrought six, five, four, and three years ago, were _permanent_. And most of these patients _were pronounced incurable_ when they began Warner's SAFE Remedies. Read a _few_ of thousands of testimonials. B.F. LARRABEE, 42 Chester Square, Boston, Mass., in 1879 was pronounced incurable of acute Bright's Disease. From 1880 to 1882 he used over 200 bottles of Warner's Safe Cure, and October 6th, 1884, he said that his cure was as permanent as surprising. REV. S.P. SMITH, Marblehead, Mass., after years of suffering from Bilious attacks and Gall Stones, began Warner's Safe Cure in 1882 and in June, 1884, reported that he had had no trouble since. HON. N.A. PLYMPTON, Worcester, Mass., in 1880 suffered frightful tortures from Gravel of the Kidneys; failing of relief otherwise he used a few bottles of Warner's Safe Cure and recently wrote: "It perfectly cured me, four years ago." L. Dow, Esq., 204 Columbus Ave., Boston, Mass., was cured of Kidney disorder by Warner's Safe Cure in 1882, and November 28th, 1884, he wrote that the cure was permanent.