The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic DevelopmentHertwig, Oscar
Science
The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic Development
Hertwig, Oscar
Developmental biology; Embryology; Genetics
Because, if its development be not interfered with, a definite egg
necessarily gives rise to a definite kind of animal, a complete identity
between the rudiment and the product, between cause and consequence, has
been assumed more or less consciously. The conception of the sequence has
been as if an organism caused its own development in a closed system of
forces, in a kind of organic perpetual motion. It has been overlooked that,
in the course of the development, many other conditions must be fulfilled,
as without them the product never would come from the rudiment.
That the same adults may come from the eggs depends upon the egg-cells, in
the ordinary course of events, being in similar conditions of anabolism and
katabolism, being affected by gravity, light, temperature, and so forth, in
the same way. Thus, when we are attempting to grasp the fundamental nature
of the course of organic development, we must not omit the part played by
these factors.
We may dwell for a moment upon this weighty point, as its significance is
commonly misunderstood.
The course of each organic development depends in the first place, upon the
absorption and metamorphosis of matter. Inorganic matter perpetually is
being turned into organic material to serve for the growth and development
of the rudiments. Thus, what in one stage of the development is mere
inorganic material, and an external condition of the development of the
rudiment, in the next stage is become a part of the rudiment. The food-yolk
of an egg, for instance, like the oxygen of the atmosphere, appears, in its
relation to the material of the rudiments, to be something supplied from
outside, an external condition of the development; yet it is continually
passing into the rudiments and altering them, even though the alteration
may be purely quantitative. From this follows the very simple inference
that during the course of an organic development external matter is always
being changed into internal matter, or that the rudiments are continually
growing and changing at the expense of the surroundings.
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