The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic DevelopmentHertwig, Oscar
Science
The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic Development
Hertwig, Oscar
Developmental biology; Embryology; Genetics
In the following pages I shall try to develop this view, taking, as
formerly, a few instances. I shall now proceed further with suggestions I
made in my treatise on _Old and New Theories of Development_. I start from
the conception that the ovum is an organism that multiplies by division
into numerous organisms like itself. I shall explain the gradual,
progressive organisation of the whole organism as due to the influences
upon each other of these numerous elementary organisms in each stage of the
development. I cannot regard the development of any creature as a mosaic
work. I hold that all the parts develop in connection with each other, the
development of each part always being dependent upon the development of
the whole.
The power of the egg to multiply by division is a chief and most important
factor in the production of complexity during the course of development. It
is only because the nuclear material, by a series of intricate, chemical
changes, assimilates reserve material from the egg and oxygen from the
atmosphere that it can give rise to continually increasing complexity
within itself. The increase in bulk results in a cleavage into two, four,
eight, and sixteen pieces, and so forth. The cleavage produces a constantly
changing distribution in space of the nuclear material. The two, four,
eight, and sixteen nuclei that arise by division diverge from each other
and take up new positions inside the egg, in definite relations to each
other. At first the particles of the egg were arranged around the
fertilised nucleus, which was a single centre of force; they become grouped
around as many centres of forces as there are nuclei, and so become
segregated into as many cells. Clearly enough, the egg, in its
single-celled condition, changes its quality in a marked degree when it
becomes multicellular, even although the change has occurred by doubling
division.
This, so clear in the early stages of development, continues to occur
throughout the later stages of growth. The continued cell-multiplication
causes not only changes of bulk, but also from time to time changes in
quality; for each shape is bound up with definite conditions. When the
conditions alter, the organic material, by its power of reaction, changes
its shape in a corresponding fashion.
As the nature of architectural plans depends upon the properties of the
wood, stone, or iron, as they must correspond with the material to be
employed (_i.e._, the span of a roof, the construction of a bridge depend
upon the material in shape and weight), so the nature of the organic
material determines to a large extent the shapes assumed in the course of
growth.
Shape in many respects appears to be a function of growth in an organic
material.
Public-domain text, read in full here on John Shaqi.
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