But we must not conclude, as we are tempted to do, that muscle is capable of liberating as mechanical work the whole of the energy supplied to it in food, seeing that its activity is always accompanied by evolution of more heat than can be attributed to friction. If the bulb of a thermometer be inserted into a group of muscles, the instrument shows a marked rise of temperature when the muscles contract. Even though the temperature of the chamber in which an animal is placed is equal to its own, the animal makes more heat if compelled to work, notwithstanding the fact that the consequent rise of its body temperature may prove fatal. Nor can muscles dispense unlimited heat without doing mechanical work. If I am too cold, the obvious means of getting warm is jumping about. There appears to be a level of heat-production which cannot be exceeded without movement. When more heat is called for than quiescent muscles can produce, they exhibit flickering contractions, shivering, without moving the limbs. The signal for increased production is given by the skin. The skin is sensible of the amount of heat which is being lost. Exposure to cold air makes one shiver, by suddenly withdrawing heat. But an increase of temperature in the blood behind the skin has an exactly similar effect. In the first stage of fever, when the temperature of the body has risen two or three degrees, and before the system has become accustomed to this state of affairs, the skin announces to the muscles that heat is being rapidly lost. A severe shiver, termed a “rigor,” is the result. At the same time loss of heat by evaporation is checked, just as it is when the skin is cold. The sweat-glands are rendered inactive. A phenomenon which marks the nightly fall of temperature in consumptive patients is the sudden return of activity in these glands.