The Body at Work: A Treatise on the Principles of PhysiologyHill, Alex
Science
The Body at Work: A Treatise on the Principles of Physiology
Hill, Alex
Physiology
There is a danger of seeing too much in a nerve-cell when examining
it under the highest powers of the microscope, and of endeavouring to
picture in too much detail the arrangements which regulate the flow
of impulses. Its markings are so complicated as to suggest to the
mind of the observer that it is itself a microcosm—a nervous system
in miniature. Neuro-fibrillæ appear to offer many alternative paths
within the cell. It is unlikely that such a way of looking at the unit
of structure is the right one. A certain motor cell of the spinal cord
is connected by its axon with thirty or forty separate muscle-fibres;
but there is no reason for thinking that the fibres ever contract save
as a single group. The axon consists of parallel fibrillæ, but these
do not appear to be needed as separate conductors; an impulse travels
down the fascicle. It does not appear to be necessary in the case of
a motor cell, and presumably the statement holds good for the large
cells of the cerebellum and cerebrum to picture any arrangement for the
simultaneous conduction in its axon of several impulses, or for the
conduction of one impulse along one of its fibrillæ and a different
one along another. What is necessary is that this particular efferent
path Z should be accessible from every other part of the nervous
system—from A to Y. If, merely for the sake of filling the space
which would otherwise be blank in the mental picture, we imagine a
pericellular net connected by thorns with the body and dendrites of
the nerve-cell Z, then the net is the meeting-ground of all the routes
through which Z is called into action. A nerve-wave from any of the
neurones A to Y, breaking upon this net, passes along the thorns into
the protoplasm of Z.
In size a granule of the cerebellum presents a marked contrast to a
motor cell of the spinal cord; yet it is formed on essentially the
same plan. From its minute round body (about 8 µ in diameter) four or
five slender dendritic processes are drawn out. Each dendrite ends in
a little bunch of twigs, resembling fingers curved over the palm. Its
single slender axon runs towards the surface of the cortex. As the
granules lie at a considerable depth, this course is, for those which
distribute to the most superficial layers, a long one. They pass from
the granular to the molecular layer between the big cells of Purkinje.
When the axon has reached a certain level in the molecular layer, it
divides into two threads which run for a great distance, right and left.
Public-domain text, read in full here on John Shaqi.
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