The Body at Work: A Treatise on the Principles of PhysiologyHill, Alex
Science
The Body at Work: A Treatise on the Principles of Physiology
Hill, Alex
Physiology
When the tension of oxygen in lymph is less than its
tension in plasma, the former borrows from the latter. If the tension
of carbonic acid in lymph is higher than in blood, it passes to the
blood. The rapidly circulating blood at frequent intervals traverses
the lungs. The whole blood of the body is exposed to air in the lungs
once every minute. Oxygen tension being higher in pulmonary air than in
venous blood, this gas is taken up. Carbonic acid tension being higher
in venous blood than in pulmonary air, this gas escapes. The plasma in
the capillary vessels which traverse the tissues exchanges gases with
the lymph with very great rapidity.
The specific gravity of blood varies from 1·056 to 1·059. The
corpuscles are heavier than the plasma. Its reaction to test-paper is
alkaline, owing to the presence of bicarbonate of soda and disodic
phosphate. The alkalinity is greatest when the body is at rest; it is
diminished by severe muscular exercise. Blood contains about 5,000,000
red corpuscles, and 7,000 or 8,000 leucocytes, to a cubic millimetre.
Red blood-corpuscles are biconcave discs destitute of nucleus, and, so
far as can be seen, devoid of any investing membrane. Seen in profile
they appear biscuit-shaped, because the centre is hollowed out. Their
largest diameter is 7·5 micromillimetres (¹/₃₂₀₀ inch)—a measurement
of great importance to anyone who works with a microscope, because it
serves as a standard by which to estimate the size of other objects.
They are soft, but fairly tough and highly elastic. In circulating
blood a corpuscle may occasionally be seen to catch on the point where
two capillary vessels unite. It bends almost double under the pressure
of the column of corpuscles behind it, and then springs forward.
A red corpuscle is a vehicle for hæmoglobin. If blood is diluted with
water, or if it is alternately frozen and thawed, the hæmoglobin
separates from the corpuscles, which can then be seen as colourless
discs. Hæmoglobin constitutes 40 per cent. of the weight of a
moist corpuscle, or 95 per cent. of its weight after it has been
dried. This is an enormous charge for a corpuscle to carry, and the
question of how it carries it has been much discussed. It is not in
a crystalline state. A corpuscle examined by polarized light is not
doubly refractive. Microscopists know that if there were any crystals
in the corpuscle it would appear bright on a dark ground when the
Nicholl prisms are crossed. It cannot be in solution, since the water
which the corpuscle contains would not suffice to dissolve it. It must
be combined with some constituent of the corpuscle. But whether it
is uniformly distributed throughout the disc, or in a semifluid form
enclosed in spaces in a sponge-work; or whether the corpuscle is a
hollow vesicle enclosing fluid hæmoglobin—a view which was long ago
maintained, and has recently been revived—are questions which still
await further evidence.
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