Thus, by a last terrible blow, never to rise again, fell this branch of the house of Aragon, which had now reigned for sixty-five years. Frederic, its head, demanded and obtained a safe-conduct to pass into France, where Louis XII gave him the duchy of Anjou and 30,000 ducats a year, on condition that he should never quit the kingdom; and there, in fact, he died, an the 9th of September 1504. His eldest son, Dan Ferdinand, Duke of Calabria, retired to Spain, where he was permitted to marry twice, but each time with a woman who was known to be barren; and there he died in 1550. Alfonso, the second son, who had followed his father to France, died, it is said, of poison, at Grenoble, at the age of twenty-two; lastly Caesar, the third son, died at Ferrara, before he had attained his eighteenth birthday. Frederic’s daughter Charlotte married in France Nicholas, Count of Laval, governor and admiral of Brittany; a daughter was born of this marriage, Anne de Laval, who married Francois de la Trimauille. Through her those rights were transmitted to the house of La Trimouille which were used later on as a claim upon the kingdom of the Two Sicilies. The capture of Naples gave the Duke of Valentinois his liberty again; so he left the French army, after he had received fresh assurances on his own account of the king’s friendliness, and returned to the siege of Piombino, which he had been forced to interrupt. During this interval Alexander had been visiting the scenes of his son’s conquests, and traversing all the Romagna with Lucrezia, who was now consoled for her husband’s death, and had never before enjoyed quite so much favour with His Holiness; so, when she returned to Rome she no longer had separate rooms from him. The result of this recrudescence of affection was the appearance of two pontifical bulls, converting the towns of Nepi and Sermoneta into duchies: one was bestowed on Gian Borgia , an illegitimate child of the pope, who was not the son of either of his mistresses, Rosa Vanozza or Giulia Farnese, the other on Don Roderigo of Aragon, son of Lucrezia and Alfonso: the lands of the Colonna were in appanage to the two duchies. But Alexander was dreaming of yet another addition to his fortune; this was to came from a marriage between Lucrezia and Don Alfonso d’Este, son of Duke Hercules of Ferrara, in favour of which alliance Louis XII had negotiated.