185. ATROPA Belladonna. DEADLY NIGHTSHADE. The Leaves, L. E. D.-- Belladonna was first employed as an external application, in the form of fomentation, to scirrhus and cancer. It was afterwards administered internally in the same affections; and numerous cases, in which it had proved successful, were given on the authority of the German practitioners. It has been recommended, too, as a remedy in extensive ulceration, in paralysis, chronic rheumatism, epilepsy, mania, and hydrophobia, but with so little discrimination, that little reliance can be placed on the testimonies in its favour; and, in modern practice, it is little employed. It appears to have a peculiar action on the eye: hence it has been used in amaurosis; and from its power of causing dilatation of the pupil, when topically applied under the form of infusion, it has been used before performing the operation for cataract. A practice which is hazardous, as the pupil, though much dilated by the application, instantly contracts when the instrument is introduced. When given internally, its dose is from one to three grains of the dried leaves, or one grain of the inspissated juice.--Murray's Mat. Med. p. 174. I have had a cancer of the lip entirely cured by it: a scirrhosity in a woman's breast, of such kind as frequently proceeds to cancer, I have found entirely discussed by the use of it. A sore, a little below the eye, which had put on a cancerous appearance, was much mended by the internal use of the Belladonna; but the patient having learned somewhat of the poisonous nature of the medicine, refused to continue the use of it; upon which the sore grain spread, and was painful; but, upon a return to the use of the Belladonna, was again mended to a considerable degree; when the same fears again returning, the use of it was again laid aside, and with the same consequence, the sore becoming worse. Of these alternate states, connected with the alternate use of and abstinence from the Belladonna, there were several of these alterations which fell under my own observation [Footnote: See the Poisonous Plants, in a future page].--Cullen's Mat. Med. vol. ii. p. 270. 186. CARDAMINE pratensis. LADIES SMOCK. The Leaves. L. E. D.--Long ago it was employed as a diuretic; and, of late, it has been introduced in nervous diseases, as epilepsy, hysteria, choraea, asthma, &c. A dram or two of the powder is given twice or thrice a-day. It has little sensible operation. 187. CARUM Carui. CARAWAY. The Seeds. L. E. D.--These are in the number of the four greater hot seeds; and frequently employed as a stomachic and carminative in flatulent colics, and the like. Their officinal preparations are an essential oil and a spiritous water; they were used as ingredients also in the compound juniper water, tincture of sena, stomachic tincture, oxymel of garlic, electuary of bayberries and of scammony, and the cummin-seed plaster.