There are three kinds of change in the world in which we live--physical and mechanical change which goes on in time and place among the tangible bodies about us, chemical change which goes on in the world of hidden molecules and atoms of which bodies are composed, and vital change which involves the two former, but which also involves the mysterious principle or activity which we call life. Life comes and goes, but the physical and chemical orders remain. The vegetable and animal kingdoms wax and wane, or disappear entirely, but the physico-chemical forces are as indestructible as matter itself. This fugitive and evanescent character of life, the way it uses and triumphs over the material forces, setting up new chemical activities in matter, sweeping over the land-areas of the earth like a conflagration, lifting the inorganic elements up into myriads of changing and beautiful forms, instituting a vast number of new chemical processes and compounds, defying the laboratory to reproduce it or kindle its least spark--a flame that cannot exist without carbon and oxygen, but of which carbon and oxygen do not hold the secret, a fire reversed, building up instead of pulling down, in the vegetable with power to absorb and transmute the inorganic elements into leaves and fruit and tissue; in the animal with power to change the vegetable products into bone and muscle and nerve and brain, and finally into thought and consciousness; run by the solar energy and dependent upon it, yet involving something which the sunlight cannot give us; in short, an activity in matter, or in a limited part of matter, as real as the physico-chemical activity, but, unlike it, defying all analysis and explanation and all our attempts at synthesis. It is this character of life, I say, that so easily leads us to look upon it as something _ab extra_, or super-added to matter, and not an evolution from it. It has led Sir Oliver Lodge to conceive of life as a distinct entity, existing independent of matter, and it is this conception that gives the key to Henri Bergson's wonderful book, "Creative Evolution." There is possibly or probably a fourth change in matter, physical in its nature, but much more subtle and mysterious than any of the physical changes which our senses reveal to us. I refer to radioactive change, or to the atomic transformation of one element into another, such as the change of radium into helium, and the change of helium into lead--a subject that takes us to the borderland between physics and chemistry where is still debatable ground.