The Brooklyn Medical Journal. Vol. II. No. 2. Aug., 1888Various
Science
The Brooklyn Medical Journal. Vol. II. No. 2. Aug., 1888
Various
Medicine -- Periodicals
None. None. 245 cc.
Salicylic acid. 1 to 500. No sugar formed.
Salicylic acid. 1 to 1,000. No sugar formed.
Salicylic acid. 1 to 20,000. 245 cc.
Boric acid. 1 to 1,000. 245 cc.
Sodium bisulphite. 1 to 1,000. 245 cc.
Saccharine. 1 to 1,000. 18.5 cc.
Saccharine. 1 to 500. 5.6 cc.
Beta-Naphthol. 1 to 1,000. 204 cc.
Beta-Naphthol. 1 to 500. 174 cc.
Alcohol. 1 to 25. 245 cc.
Experiments with varying amounts of diastase showed that one part of
salicylic acid to 1,000 of liquid prevented the diastasic action
completely. Saccharine in the proportion of 1 to 1,000 prevented the
formation of sugar when the proportion of diastase was 1 to 1,000 of
liquid. When the proportion of diastase was reduced to 1 in 2,000,
salicylic in the proportion of 1 to 3,000 prevented the formation of
sugar. It seems, then, that the weaker the diastasic solution, the more
is its action hindered by salicylic acid, saccharine, etc. Sodium
bisulphite has little if any power of hindering diastasic power.
_Experiments with Fairchild’s Pancreatic Extract._
_Antiseptic._ _Amount._ _Fehling’s Solution required._
None. None. 78 cc.
Salicylic acid. 1 to 1,000. No sugar formed.
Saccharine. 1 to 1,000. No sugar formed.
Beta-Naphthol. 1 to 1,000. 78 cc.
Boric acid. 1 to 1,000. 78 cc.
Sodium bisulphite. 1 to 1,000. 80 cc.
The tests were made with 0.2 grams of the extract.
It seems from these experiments that salicylic acid and saccharine, in
the proportions used, entirely prevent the action of pancreatic ferment
upon starch.
In similar experiments with saccharated pepsine with hydrochloric acid,
except that the temperature was kept at 105° F., sodium bisulphite and
boric acid were without effect.
Saccharine and salicylic acid had a slightly retarding action.
Beta-naphthol almost entirely prevented the action.
With pancreatic digestion of albumen the results were practically the
same, but the retarding action of the salicylic acid and saccharine was
not quite so well marked.
From these experiments it will be seen that salicylic acid prevents the
conversion of starch into sugar under the influence of either diastase
or pancreatic extract, but does not seriously interfere with peptic or
pancreatic digestion of albumen. Saccharine holds about the same
relation as salicylic acid.
Sodium bisulphite and boric acid are practically without retarding
effect.
Beta-naphthol decidedly interferes with the formation of sugar by
diastase, but not with the action of pancreatic extract on starch.
Public-domain text, read in full here on John Shaqi.
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