With the progressive refinement of microscopic technique, it has become
apparent that the law of genetic continuity applies not merely to the
cell as a whole and to its major parts, the nucleus and the cell-body,
but also to the minor components or organelles, which are seen to
be individually self-perpetuating by means of growth and division.
The typical cell nucleus, as is well known, is a spherical vesicle
containing a semisolid, diphasic network of basichromatin (formerly
“chromatin”) and oxychromatin (linin) suspended in more fluid medium
or ground called nuclear sap. When the cell is about to divide, the
basichromatin resolves itself into a definite number of short threads
called chromosomes. Now, Boveri found that, in the normal process of
cell-division known as mitosis, these nuclear threads or chromosomes
are each split lengthwise and divided into two exactly equivalent
halves, the resulting halves being distributed in equal number to the
two daughter-cells produced by the division of the original cell.
Hence, in the year 1903, Boveri added a fourth article to the law of
genetic vital continuity, namely: _Omne chromosoma ex chromosomate_.
But the law in question applies to cytoplasmic as well as nuclear
components. In physical appearance, the cell-body or cytoplasm
resembles an emulsion with a clear semiliquid external phase called
hyaloplasm and an internal phase consisting mainly of large spheres
called macrosomes and minute particles called microsomes, all of which,
together with numerous other formed bodies, are suspended in the clear
hyaloplasm (hyaline ground-substance). Now certain of these cytoplasmic
components have long been known to be _self-perpetuating_ by means
of growth and division, maintaining their continuity from cell to
cell. The plastids of plant cells, for example, divide at the time of
cell-division, although their distribution to the daughter-cells does
not appear to be as definite and regular as that which obtains in the
case of the chromosomes. Similarly, the centrioles or division-foci
of animal cells are self-propagating by division, but here the
distribution to the daughter-cells is exactly equivalent and not at
random as in the case of plastids. In the light of recent research
it looks as though two other types of cytoplasmic organelles must be
added to the list of cellular components, which are individually
self-perpetuating by growth and division, namely, the chondriosomes
and the Golgi bodies—“both mitochondria and Golgi bodies are able to
assimilate, grow, and divide in the cytoplasm.” (Gatenby.) Wilson is
of opinion that the law of genetic continuity may have to be extended
even to those minute granules and particles of the cytosome, which were
formerly thought to arise _de novo_ in the apparently structureless
hyaloplasm. Speaking of the emulsified appearance of the starfish and
sea urchin eggs, he tells us that their protoplasm shows “a structure
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