Loeb’s experiments in artificial parthenogenesis have been
sensationally misinterpreted by some as an artificial production of
life. What Jacques Loeb really did was to initiate development in an
unfertilized egg by the use of chemical and physical excitants. The
writer has repeated these experiments with the unfertilized eggs of the
common sea urchin, _Arbacia punctulata_, using very dilute butyric acid
and hypertonic sea water as stimulants. Cleavage had started within an
hour and a half after the completion of the aforesaid treatment, and
the eggs were in the gastrula stage by the following morning (9 hours
later). In three days, good specimens of the larval stage known as the
pluteus could be found swimming in the normal sea water to which the
eggs had been transferred from the hypertonic solution. Since mature
sea urchin eggs undergo reduction before insemination takes place,
the larval sea urchins arising from these artificially activated
eggs had the reduced or haploid number of chromosomes instead of the
diploid number possessed by normal larvæ arising from eggs activated
by the sperm. For, in fertilization, the sperm not only activates the
egg, but is also the means of securing biparental inheritance, by
contributing its quota of chromosomes to the zygotic complex. Hence,
it is only in the former function, _i. e._ of initiating cleavage in
the egg, that a chemical excitant can replace the sperm. In any case,
it is evident that these experiments do not constitute an exception
to the law of genetic cellular continuity. The artificially activated
egg comes from the ovaries of a living female sea urchin, and in this
there is small consolation for the exponent of abiogenesis. The terse
comment of an old Irish Jesuit sizes up the situation very aptly: “The
Blue Flame Factory,” he said, “has announced another discovery of the
secret of life. A scientist made an egg and hatched an egg. The only
unfortunate thing was that the egg he hatched was not the egg he made.”
How an experiment of this sort could be interpreted as an artificial
production of life is a mystery. The only plausible explanation is that
given by Professor Wilson, who traces it to the popular superstition
that the egg is a lifeless substrate, which is animated by the sperm.
The idea owes its origin to the spermists of the 17th century, who
defended this doctrine against the older school of preformationists
known as ovists. It is now, however, an embryological commonplace that
egg and sperm are both equally cellular, equally protoplasmic, and
equally vital.
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account