To begin with, it is not to a single dispersed particle or ultramicron
that protoplasm has been likened, but to an emulsion, comprising both
the dispersed particles and the dispersing medium, or, in other words,
to the colloidal system as a whole. Moreover, even there the analogy
is far from being perfect, and is confined exclusively, as Wilson has
pointed out, to a rough similarity of structure and appearance. The
colloidal system is obviously a mere _aggregate_ and not a _natural
unit_ like the cell, and its dispersed particles (ultramicrons) do
not multiply and perpetuate themselves by growth and division as do
the living components or formed bodies of the cell. As for the single
ultramicron or multimolecule of a colloidal solution, it may, indeed,
be a natural unit, but it only resembles the cell in the sense that,
like the latter, it is a complex of constituent molecules. Here,
however, all resemblance ceases; for the ultramicron does not display
the typically vital power of self-perpetuation by growth and division,
which, as we have seen, is characteristic not only of the cell as a
whole, but of its single components or organelles. Certainly, the
distinctive phenomena of colloidal systems cannot be interpreted as
processes of multiplication. There is nothing suggestive of this vital
phenomenon in the reversal of phase, which is caused by the addition
of electrolytes to oil emulsions, or in gelation, which is caused by
a change of temperature in certain hydrophilic colloids. Thus the
addition of the salt of a bivalent cation (_e.g._ CaCl₂ or BaCl₂)
to an oil-in-water emulsion (if soap is used as the emulsifier) will
cause the external or continuous phase (water) to become the internal
or discontinuous phase. Vice versa, a water-in-oil emulsion can be
reversed into an oil-in-water emulsion, under the same conditions,
by the addition of the salt of a monovalent cation (_e. g._ NaOH).
Solutions of hydrophilic colloids, like gelatine or agar-agar, can
be made to “set” from the semifluid state of a hydrosol into the
semisolid state of a hydrogel, by lowering the temperature, after
which the opposite effect can be brought about by again raising the
temperature. In white of egg, however, once gelation has taken place,
through the agency of heat, it is impossible to reconvert the “gel”
into a “sol” (solution). In such phenomena, it is, perhaps, possible
to see a certain parallelism with some processes taking place in the
cell, _e. g._ the osmotic processes of absorption and excretion, but to
construe them as evidence of propagation by growth and division would
be preposterous.
Public-domain text, read in full here on John Shaqi.
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