This being the case, it is much more reasonable to interpret the thymus
as an ontogenetic (embryonic), rather than a phylogenetic (racial)
rudiment. It has been observed that, in the case of reptiles which
lack definite lymphatic glands (which function in man as formative
centers of lymphocytes or white blood corpuscles), the thymus is
extraordinarily developed and abounds in lymphoid cells. It has also
been observed that the formation of lymphocytes in the lymphatic
glands is regulated by the digestive process; for, after digestion,
the activity of these glands increases and the formation of leucocytes
is accelerated. Since, then, the lymphatic glands appear to require
the stimulus of the digestive process to incite them to action, it
is clear that in the fœtus, which lacks the digestive process, the
lymphatic glands will not be stimulated to action, and that the task
of furnishing lymphocytes will devolve upon the thymus. After birth,
the digestive process commences and the lymphatic glands become active
in response to this stimulus. As the function of forming lymphocytes
is transferred from the thymus to the lymphatic glands, the former is
gradually deprived of its importance, and, in the interest of organic
economy, it begins to atrophy, until, at the end of the child’s second
year, or, at latest, when the child has reached sexual maturity,
nothing but a reduced vestige remains of this once functional organ.
“The thymus,” says Starling, “forms two large masses in the anterior
mediastinum which in man grow up to the second year of life and then
rapidly diminish, so that only traces are to be found at puberty. It
contains a large amount of lymphatic tissue and is therefore often
associated with the lymphatic glands as the seat of the formation of
lymph corpuscles.... In certain cases of arrested development or of
general weakness in young people, the thymus has been found to be
persistent.” (“Physiology,” 3rd ed., 1920, p. 1245.)
Public-domain text, read in full here on John Shaqi.
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