Syphilis is the only disease transmitted to the offspring in full virulence, killing them outright, or blighting their normal development. When the father alone is infected the mortality is about 38%. When the mother also becomes infected the mortality averages from 60% to 80%. Fully ⅓ of all infected children die within the first six months. Even when the subjects of inherited syphilis successfully run the gauntlet of diseases incident to infancy and childhood they do not always escape the effects of the parental disease. They are subject to various organic defects or stigma of degeneration, as they are termed. A final result of hereditary syphilis is the inability to procreate healthy children. If the subjects of inherited syphilis grow up and marry they are liable to transmit the same class of organic defects to the third generation. _FEWER AND BETTER BABIES, OR THE LIMITATION OF OFFSPRING. Wm. J. Robinson, M.D., Chief of the Department Genito-Urinary Diseases and Dermatology, Bronx Hospital and Dispensary; Fellow of the American Medical Association and of the New York Academy of Medicine._ There are thousands of syphilitic men and women who are perfectly safe as far as their partner is concerned, but are not safe enough to become parents. They cannot infect, but they must not give birth to children for fear that the children may have the taint in them. The use of preventives settles this problem and saves the world from thousands of pitiable hereditary syphilitics. P. 126. _MEDICAL GYNECOLOGY. Howard A. Kelly._ Two fundamental characteristics, contagiousness and susceptibility of hereditary transmission, give to syphilis an altogether special importance in relation to marriage. The statement has been made that syphilis constitutes a far greater danger to Society and the race than to the individual. The chief significance of syphilis as a racial danger comes from its hereditary effects. In addition, hereditary syphilis undoubtedly creates a terrain, or soil, favorable for the reception and germination of tubercle bacilli, and perhaps other bacilli. It does this by impoverishing the organism and diminishing the capacity of resistance against microbic invasion. From the view point of race perpetuation, syphilis is antagonistic to all the family represents in our social system. The essential aim of marriage is not simply the procreation of children, but of children born in conditions of vital health and physical vigor. The effect of syphilis is to so vitiate the procreative process as to produce abortions, or else a race of inferior beings, endowed with defects and infirmities and unfit for the struggle of life. It is this pernicious effect of syphilis upon the offspring which gives to the disease a dominant influence as a factor in the degeneration and depopulation of the race. P. 444.