"It is located on Fifth and Sixth streets, between Avenues B and C, being the two brick dwellings Nos. 407 and 409 Fifth street, and the one immediately in the rear of No. 173 Sixth street. It is under the care of the 'Sisters of the Poor of Saint Francis,' and is a free hospital for both sexes, without distinction as to creed, and its inmates comprise Catholics, Protestants, and Jews. The means for purchasing this property were obtained by the solicitations of the sisters from door to door. I think the order of Saint Francis originated in Germany, where it still has its headquarters. Most of the sisters here are German, though there are certainly one or two exceptions. The accommodations are altogether inadequate, and not at all well adapted to the purposes. The patients are cheerful and happy, and there is every evidence that all the efforts of these sisters arise from the most pure and unselfish motives, and that there is not the least constraint in regard to religious matters resting upon the inmates. There is a very small chapel in the establishment, the attendance upon which is wholly voluntary. The commonest services are performed by the sisters, and, Puritan Protestant as I was educated, I could but admire the devotion and kindness of these women. I believe their charity is a true and unselfish one; that they are animated by his Spirit who went about doing good, and they should be well supported in their work. "The patients are of all ages and nationalities, perhaps a more than usual average of Germans. I was particularly interested in two of the wards, one for the 'grandfathers' and the other for the 'grandmothers,' both of them filled with quite aged people. Many of the patients seemed to be incurables, and have a permanent home in the Saint Francis. The good sisters have secured a large plot of ground on which they purpose erecting a building of much greater capacity than those they now occupy, and thoroughly adapted to the objects of the institution. For this object they will need large contributions, which I earnestly hope will be promptly furnished. The following is a general summary of the past year: Number of patients treated in Hospital, (males, 484; females, 108).............593 Discharged, cured or improved............423 Died......................................88 Remaining December 31, 1867...............81