“At first the victim feels devouring thirst, great feverish action, and a singular trembling in every limb; stiffness and a certain weakness in the joints; a great weight on the chest like that caused by sorrow; a rush of blood to the brain; fatigue and drowsiness, and other disagreeable symptoms which now escape my memory. The entire nervous system is then struck, as it were, with insensibility to such a degree that a sharp instrument or a needle, or even the blade of a knife, buried in the fleshy parts or thrust through the tendons and cartilage, causes the leper little or no pain. Some poor creature, with calm indifference, will place his arm or leg on a mass of burning wood and tar, and let it remain there until the entire limb, bones and all, is consumed; yet the leper feels no pain, and may sleep through it all as quietly as if in his bed.” In another letter the abbé gives the following example of this astonishing insensibility: “One of these afflicted beings who died at the lazaretto, and to whom I administered the last sacraments, lay down to sleep near a hot fire; in his slumbers he thrust one arm and hand into the flames, but continued to sleep. The overpowering smell of burning flesh awakened one of his companions, who succeeded in saving his life.” One of the nuns says: “Since we reached Tracadie two of the patients have burned their hands severely, and were totally unconscious of having done so until I dressed the wounds myself.” In regard to this torpidity of the system, M. Gauvreau remarks that it is but temporary, but he knows not its duration; and the nun adds that the torpidity is not invariable with all the patients, and with some only in a portion of the body. In certain individuals it is only in the legs; in others, in the hands alone; but all complain of numbness like that of paralysis. “By degrees,” says M. Gauvreau, “the unnatural whiteness of the skin disappears, and spots of a light yellow are to be seen. These spots in some cases are small and about the size of a dollar-piece. When of this character, they appear at first with a certain regularity of arrangement, and in places corresponding with each other, as on the two arms and shoulders—more generally, however, on the breast. They are distinct, but by degrees the poison makes its way throughout the vitals; the spots enlarge, approach each other, and, when at last united, the body of the sick man becomes a mass of corruption. Then the limbs swell, afterward portions of the body, the hands, and the feet; and when the skin can bear no further tension it breaks, and running sores cover the patient, who is repulsive and disgusting to the last degree.