Defeat cut John Randolph more deeply than it did David Crockett under similar circumstances. Randolph retired to his cabin and brooded; misanthropy gnawed like the vulture at the vitals of Prometheus bound. He longed for human sympathy, and was too proud to accept of it when proffered. It was during this season of disappointment and isolation that his severest religious discipline and the hope of conversion came; then also came the last sundering of his hopes of a lineal successor. “This business of living,” he said, “is dull work. I possess so little of pagan philosophy or of Christian patience as to be frequently driven to despair. * * I look forward without hope. * * I have been living in a world [in Washington] without souls, until my heart is dry as a chip, and cold as a dog’s nose.” In 1815 Randolph rode into Congress again on the wave of reaction against the war and its burdens, and remained in the House until 1826, when he was elected to the Senate to fill a vacancy. His antagonism against Henry Clay reached a dangerous point in the struggle over the Missouri Compromise of 1820. Randolph went to England in 1822. He took with him large quantities of books and magazines to be bound, as he would not “patronize our Yankee task-masters, who have caused such a heavy duty to be imposed on foreign books. I shall employ John Bull to bind my books until the time arrives when they can be properly done south of Mason and Dixon’s line.” He was received with much honor by all classes in England, where his stout championship of English ideas was well known. His singular appearance was heightened by his very great emaciation, and by a big fur cap with a long fore-piece which he wore. But the splendid intellect, fine manners, and brilliant conversational powers which shone out of this grotesqueness, made him even more noted. The issue of the Presidential election of 1825 was the occasion of the Randolph-Clay duel. There had been no choice by the people, and the election went to the House of Representatives. Adams, Crawford, Clay and Jackson were the candidates. Clay’s friends threw the election to John Quincy Adams. When the latter made up his cabinet, Clay’s name appeared at the head, as Secretary of State. The disappointed friends of Jackson and Crawford immediately made charges of a bargain between Adams and Clay, but no one dwelt on it with such persistence and bitterness of invective as Randolph. In a speech in the Senate in 1826, he referred to Adams and Clay as “the coalition of Blifil and Black George—the combination, unheard of till then, of the _Puritan_ with the _blackleg_.” He also charged Clay with forging or falsifying certain state documents which had been furnished the Senate. A challenge from Clay promptly followed, and was as promptly accepted, Randolph refusing to disclaim any personal meaning as to Clay.