The accounts of the last fearful disaster are yet incomplete, and may not all be verified. The latest, and apparently most reliable reports, place it among the most terrible calamities known in the history of the race, since the deluge. The earth trembled and shook—rocks were rent—buildings tumbled in ruins. A large part of the city, full of wealth and life, sank out of sight. Tidal waves carried destruction along the coast. Volcanoes belched forth smoke, ashes and lava, overspreading fertile valleys; and when the sulphurous clouds that hung over them, black as night, were lifted, turbulent waters rolled over fifty square miles of pasture lands that the day before were covered with flocks, and the homes of men. It is estimated that seventy-five thousand people perished. It may be a few thousand less, or more, as there are yet no data from which to form more than a proximate estimate. The whole number will not be known till the graves and the sea give up their dead. LOW SPIRITS. By J. MORTIMER GRANVILLE. There is enough in the daily experience of life to depress the feelings and rob the mind of its buoyancy, without having to encounter lowness of spirits as a besetting mental state or malady. Nevertheless, it so frequently assumes the character of an affection essentially morbid, attacks individuals who are not naturally disposed to despondency, and gives so many unmistakable proofs of its close relations with the health of the physical organism, that it must needs be included in the category of disease. The constitutional melancholy which distinguishes certain types of character and development, is a setting in the minor key rather than depression. Within the compass of a lower range, individuals of this class exhibit as many changes of mood as those whose temperament is, so to say, pitched higher, and who therefore seem to be capable of greater elation. It is important to ascertain at the outset whether a particular person upon whom interest may be centered is not naturally characterized by this restrained or reserved tone of feeling! Unhealthy conditions of mind are generally to be recognized by the circumstance that they offer a contrast to some previous state. The movable, excitable temperament may become fixed and seemingly unimpressionable, the self-possessed begin to be irritable, the calm, passionate. It is the _change_ that attracts attention, and when low spirits come to afflict a mind wont to exhibit resilience and joyousness, there must be a cause for the altered tone, and prudence will enjoin watchfulness. Mischief may be done unwittingly by trying to stimulate the uncontrollable emotions.