The state of mental collapse must be allowed to pass; but here comes the difficulty; the moment reaction takes place, as shown by a slight raising of the cloud, it will be too late to interfere. The mind will then have entered on another phase not less morbid than the depression which it has replaced. There is no certain indication of the right moment to make the effort for the relief of a sufferer from this progressive malady. The way to help is to watch the changes of temperament narrowly, and, guided by time rather than symptoms, to present some new object of interest—a trip, an enterprise, a congenial task—at the moment which immediately precedes the recovery. The soul lies brooding—it is about to wake; the precise time can be foreknown only by watching the course of previous attacks; whatever engrosses the rousing faculties most powerfully on waking, will probably hold them for awhile. It is a struggle between good and healthy influences on the one hand, and evil and morbid on the other. If it be earnestly desired to rescue the sufferer, the right method must be pursued, and wrong and mischief-working procedures—among which preaching, persuading, moralizing, and rallying are the worst and most hurtful—ought to be carefully avoided. When the thoughts are revived and the faculties rebound, they must be kept engaged with cheering and healthful subjects. There is no greater error than to suppose good has been accomplished when a melancholic patient has been simply aroused. The apparently bright interval of a malady of this class is even more perilous than the period of exhaustion and lowness. The moment the mind resumes the active state, it generally resumes the work of self-destruction. The worst mischief is wrought in the so-called lucid interval. The consciousness must be absorbed and busied with healthful exercise, or it will re-engage in the morbid process which culminates in depression. The problem is to keep off the next collapse, and this can be accomplished only by obviating the unhealthy excitement by which it is commonly preceded and produced. Healthy activity promotes nutrition, and replenishes the strength of mind and body alike; all action that does not improve the quality of the organ acting, deteriorates it and tends to prevent normal function. VEGETABLE VILLAINS. By R. TURNER. THE LARGER FUNGI.