Eaton, Dorman B. (Dorman Bridgman), 1823-1899; Public health -- New York (State) -- New York; Sanitation -- New York (State) -- New York
This statement requires the following explanation, viz., a bacterium in
a quiescent state is harmless; everyone has within his body innumerable
bacteria, as the tubercle and typhoid bacilli; but they are inert, and
hence innocuous. It is only when they find their proper food, decaying
matter, that they begin to multiply, and in that act they secret a
poison, toxin, which is absorbed, and, entering the circulation, causes
in the individual a special class of symptoms peculiar to that toxin,
or poison.
These symptoms constitute a disease, the technical name of which is
usually fanciful, depending on some feature of the symptoms, but
explaining nothing as to its essential nature.
For example, the typhoid bacillus finds its food in certain minute
glands of the small bowels. If these glands are in a perfectly healthy
state when the bacillus enters the digestive tract, the germ will pass
over them and disappear from the body perfectly harmless. But if the
bacillus finds its appropriate food--dead or decomposing matter--in
the glands, it at once takes up its abode in them and “begins
housekeeping;” that is, it begins to multiply according to the method
of fission of its cell and rate of multiplication, already described.
During this process the multiplying cells excrete a toxin, which,
being absorbed, creates a fever, the result of a true blood poisoning.
This fever is called typhoid, because its prominent symptom, stupor,
resembles that of typhus fever. The name, therefore, signifies nothing
as to the nature of the disease.
[Sidenote: The Toxin Secreted]
The poisoning of the body by the excreted toxin of the multiplying
cells, which is simply plant food, occurs because it is removed only in
part by the digestive organs, the circulation that conveys it to the
other eliminating organs being efficient for that purpose. Could all
of this toxin be removed as fast as it is excreted, and not enter the
circulation, there would be no fever.
The termination of this process must be either the death of the colony
from exhaustion of the food supply in the glands, or the exhaustion
of the patient by the excess of toxins that accumulate in the body.
As the activity of the bacillus depends upon the food supplied, the
severity and length of the fever varies in different individuals. Some
are immune, because the glands that furnish the food of the typhoid
bacillus are in a state of high health; others have a brief and mild
attack, because the food supply is scant owing to a slight impairment
of the integrity of the glands; but with a considerable number in every
epidemic the food is ample to sustain the creation of an immense colony
of bacilli which destroys the victim by an overdose of poison.
Public-domain text, read in full here on John Shaqi.
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