The commonwealth of cells : $b Some popular essays on human physiologySpurrell, H. G. F. (Herbert George Flaxman)
Science
The commonwealth of cells : $b Some popular essays on human physiology
Spurrell, H. G. F. (Herbert George Flaxman)
Human physiology
The reason why the body can only last a certain time, in spite of the
many quacks with recipes for immortality—recipes including such items
as the avoidance of all trouble, worry, or work—must remain a secret
until we know the chemical basis of life. It seems to lie in the cell.
If a unicellular organism, as described above, be placed in a vessel
of sterilized water and left to live alone under otherwise ideal
conditions, it will start dividing and multiplying, as though it meant to
reproduce itself indefinitely. After a time, however, the shoal begins
to deteriorate; each successive generation is feebler than the last, and
eventually all die. If, however, before this happens one of the effete
cells be placed in another vessel with a similar individual derived from
a different ancestor, the two will fuse and form a single fresh animal
with entirely restored vigour, ready to multiply to the same extent as
either of its original ancestors. A few individuals of a different stock
will in this way revivify the whole brood.
There is, therefore, evidently something in the cell which wears out
after it has divided a certain number of times—something which must be
restored by blending with cells of another strain. What this is we do not
know, and perhaps never shall. The most we know is that it seems to be
something inherent in the nucleus, not the main body of protoplasm of the
cell, for some unicellular animals do not fuse, under the circumstances
related above, but exchange only pieces of their nuclei, and yet derive
the advantages of mutually increased vitality. But if we apply the fact
to our conception of the body as a vast colony of cells with a common
origin, we find that it has an important bearing upon the duration of its
life.
The single eggcell which gave rise to our schematic embryo in Diagram
3, Fig. 1, was formed by the fusion of two cells shed by two distinct
animals. How this one cell grows and multiplies by division is roughly
shown in the diagram and those immediately following it; but though the
cells do not separate, but hang together and form a body, it is obvious
that the colony only amounts to a shoal of unicellular organisms, like
that described above as growing weaker with each successive division
unless blended with individuals of a different stock. This cannot be done
in the body; what would become of our individuality even if such a thing
were possible? The body can help to give rise to new bodies, but its own
tissues must wear out, and when the colony of cells is exhausted it must
die. Careful diet and regular habits, the minimum of wear and tear, may
enable the body to run its full term; but they cannot lengthen the lease
of life.
Public-domain text, read in full here on John Shaqi.
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