Give it the PILLS in large doses to sweep these vile parasites from the body. Now turn again and see the ruddy bloom of childhood. Is it nothing to do these things? Nay, are they not the marvel of this age? And yet they are done around you every day. Have you the less serious symptoms of these distempers, they are the easier cured. Jaundice, Costiveness, Headache, Sideache, Heartburn. Foul Stomach, Nausea, Pain in the Bowels, Flatulency, Loss of Appetite, King's Evil, Neuralgia, Gout, and kindred complaints all arise from the derangements which these PILLS rapidly cure. Take them perseveringly, and under the counsel of a good physician if you can; if not take them judiciously by such advice as we give you, and the distressing dangerous diseases they cure, which afflict so many millions of the human race, are cast out like the devils of old--they must burrow in the brutes and in the sea. Prepared by DE. J. C. AYER, & CO., PRACTICAL AND ANALYTICAL CHEMISTS, LOWELL, MASS., [Illustration] And Sold by all Druggists.[Illustration] * * * * * THE ANNUAL CYCLOPÆDIA AND REGISTER OF IMPORTANT EVENTS, OF THE YEAR 1861: EMBRACING POLITICAL, CIVIL, MILITARY, AND SOCIAL AFFAIRS; PUBLIC DOCUMENTS; BIOGRAPHY; STATISTICS; COMMERCE; FINANCE; LITERATURE; SCIENCE; AGRICULTURE, AND MECHANICAL INDUSTRY. This is a Cyclopædia of what took place during the year 1861. It comprises not only all the subjects peculiar to a general work, but also the political and military events of the conflict in the United States. It shows the political principles involved, with the arguments of their respective advocates and opponents; the movements of the leaders of secession, from their first acts to the close of the year; including the proceedings, step by step, of each of the Southern States; the organization of the Confederate States; the principles upon which that organization was founded; their civil and commercial regulations; the efforts to fill their treasury and to organize and equip vast armies; the counteracting movements of the United States; the organization and equipment of its army and navy; together with all the original documents, from the Messages of the respective Presidents; the instructions of Cabinet officers; the Messages and Proclamations of Governors; the important acts and debates of the United States and Confederate Congresses; the acts of State Legislatures; the Proclamations of Commanding Officers; the contributions of men and money from each State, North and South; and the details of every battle and every skirmish involving a loss of life. The events connected with Privateering, suspension of the writ of Habeas Corpus, Martial Law, Blockade, &c., are related in detail.