In investigating closely the different parts of the city, with reference to future movements for their benefit, I soon came to know certain centres of crime and misery, until every lane and alley, with its filth and wretchedness and vice, became familiar as the lanes of a country homestead to its owner. There was the infamous German "Rag-pickers' Den," in Pitt and Willett Streets--double rows of houses, flaunting with dirty banners, and the yards heaped up with bones and refuse, where cholera raged unchecked in its previous invasion. Here the wild life of the children soon made them outcasts and thieves. Then came the murderous blocks in Cherry and Water Streets, where so many dark crimes were continually committed, and where the little girls who flitted about with baskets and wrapped in old shawls became familiar with vice before they were out of childhood. There were the thieves' Lodging-houses' in the lower wards, where the street-boys were trained by older pickpockets and burglars for their nefarious callings; the low immigrant boarding-houses and vile cellars of the First Ward, educating a youthful population for courses of guilt; the notorious rogues' den in Laurens Street--"Rotten Row"--where, it was said, no drove of animals could pass by and keep its numbers intact; and, farther above, the community of young garroters and burglars around Hamersley Street and Cottage Place. And, still more north, the dreadful population of youthful ruffians and degraded men and women in "Poverty Lane," near Sixteenth and Seventeenth streets and Ninth Avenue, which subsequently ripened into the infamous "Nineteenth-street Gang." On the east side, again, was "Dutch Hill," near Forty-second Street, the squatters' village, whence issued so many of the little peddlers of the city, and the Eleventh Ward and "Corlear's Hook," where the "copper-pickers," and young wood-stealers, and the thieves who beset the ship-yards congregated; while below, in the Sixth Ward, was the Italian quarter, where houses could be seen crowded with children, monkeys, dogs, and all the appurtenances of the corps of organ-grinders, harpers, and the little Italian street-sweepers, who then, ignorant and untrained, wandered through our down-town streets and alleys. Near each one of these "fever nests," and centres of ignorance, crime, and poverty, it was our hope and aim eventually to place some agency which should be a moral and physical disinfectant--a seed of reform and improvement amid the wilderness of vice and degradation. It seemed a too enthusiastic hope to be realized; and, at times, the waves of misery and guilt through these dark places appeared too overwhelming and irresistible for any one effort or association of efforts to be able to stem or oppose them. How the somewhat ardent hope was realized, and the plan carried out, will appear hereafter. The first special effort that we put forth was the providing of work for these children, by opening