The diagnostics and treatment of tropical diseasesStitt, E. R. (Edward Rhodes)
Science
The diagnostics and treatment of tropical diseases
Stitt, E. R. (Edward Rhodes)
Tropical medicine
In cases of amoebic dysentery, the diarrhoeal attacks, which at
times occur, are often associated with an abundance of flagellates,
which may well be the cause of the complication. Cases of dysenteric
diarrhoea have been reported from Gallipoli in which _Lamblia
(Giardia)_ were apparently the only parasites involved. Such stools
are often of a yellow ochre color. Relapses are common features
of _Lamblia_ infections. _Lamblia_ is an inhabitant of the upper
intestine while _Trichomonas_ and _Chilomastix_ belong to the
large intestine, especially in the region of the caecum. While
these last named flagellates are often found in the stools of those
convalescent from dysentery there is a general opinion that they
are nonpathogenic. These organisms may be present in diarrhoeal
conditions in which case it is common to designate such diarrhoeas as
flagellate diarrhoeas. Fantham and Porter have reported 187 cases of
pure lambliasis.
In diagnosis it is important to recognize the encysted _Lamblia_.
These are oval cysts, about 10 × 7µ and show a curved central line,
with two lateral dots. When stained these dots show as chromatin
areas. These cysts may be found in the faeces in great numbers. The
vegetative _Lamblia_ has 4 pairs of flagella, is about 15µ long and
has a tumbling motion. Calomel alone or calomel and ipecac give
good results at times. Enemata of organic silver salts may be of
benefit.
Porter recommends bismuth salicylate. Low has noted the tendency of
lambliasis to recur and thinks many of the reported cases of cures
are only temporary. His experience with bismuth, salol, thymol and
cyllin has not been encouraging.
It is well known that lambliasis is of rather frequent occurrence
in mice and rats so that these rodents may be factors in spreading
the infection through the agency of their faeces deposited about
human food.
Of other drugs recommended in treatment Dobell and Low have had no
success with methylene blue, turpentine or beta-naphthol. These
authors failed to find any increase in either large mononuclears or
eosinophiles in a case of the infection.
Since Lamblia inhabit the upper parts of the small intestine, it
may be that the administration of drugs by the duodenal tube will
prove an effective method of treatment. Owens reports successful
results in the treatment of amoebic dysentery from ipecac so
administered. Stiles has recommended sulphur in lambliasis.
3. Ciliate dysenteries (_Balantidium coli_).
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