We prescribed forty grains in a roll of butter for a worthless cur a short time since, which, as expected, produced great anxiety, difficulty of respiration, severe vomiting, tremors, spasmodic twitchings of the muscles, convulsions, and ultimate death in the course of half an hour. This powerful drug acts by causing a spasmodic stricture of the muscles engaged in respiration, as no signs of inflammation are observable in the stomach and other organs after death. Spirits of turpentine, another remedy both simple and innocent in its operations upon the human economy, and so frequently prescribed for the expulsion of worms from the bowels, is a dangerous medicine for a dog, and will often in very small quantities prove fatal. Aloes, a medicine more extensively used in canine pathology than any other in the materia medica, is also very peculiar in its operations upon these animals, they being able to bear immense doses of it, in fact quite sufficient to produce death if given to a hearty man. Thus we might continue to enumerate other drugs which we have ascertained, from practical observation as well as the experiments of other, to exercise a peculiar action on the vital functions of the whole canine race, quite at variance with that common to both man and the other domestic animals. In combating with the diseases of animals, the veterinary surgeon has more to contend with than the regular physician, and, in fact, should possess a knowledge and habit of observation even superior to the former; although the responsibility of his calling, in a moral sense, is much inferior to that of the other, as the importance of animal existence, under no circumstances, can be placed in comparison with that of human life: still acuteness of observation alone can direct him to the main cause of suffering in the brute creation, as the animal, though groaning under the most severe pains, cannot by any word of explanation point out to us the seat, the probable cause, or peculiar characteristics of such pain. We see that our dog is ill, he refuses his food, retires gloomily to his house, looks sullen, breathes heavy, is no longer delighted at our call. We cannot question him as to his feelings, or ask him to point out the particular region of his sufferings; we watch his motions, study his actions, and rely for our diagnosis upon general symptoms deduced from close observation. Besides these external ocular evidences of morbid action, we have, as in the human subject, guides to direct us in forming a just opinion as to the nature of a dog's indisposition. The state of the circulation is the first thing that should command our particular attention. The pulse of dogs in health varies from one hundred to one hundred and twenty strokes per minute, according to the size and peculiar temperament of the animal, being more frequent in the small breeds. The standard of the setter, pointer, hound, &c., may be stated at one hundred and five.