Mr. Dupuy has given a valuable account of the knowledge we possess of the diseases of the spinal marrow in our domestic quadrupeds. He has proved: 1. That in our domestic animals the spinal marrow is scarcely ever affected through the whole of its course. 2. That the dorsal and lumbar regions are the parts oftenest affected. 3. That inflammation of the spinal marrow of these regions always produces palsy, more or less complete, of the abdominal members. 4. That, in some cases, this inflammation is limited to the inferior or superior parts of the spinal marrow, and that there is loss only of feeling or of motion. 5. That sometimes animals die of palsy without any organic lesion. [Blows on the head, producing effusion on the brain, poisoning by lead, inflammation of the spinal marrow, affections of the nerves, caries of the spine, costiveness and affections of the bowels, are all productive of palsy. If the disease proceeds from rheumatism, or other inflammatory affections, independent of any organic lesion, the disease, if taken early, is not difficult to overcome in the young subject. Warm baths, bleeding, purging, and stimulating applications to the parts and along the spine, will answer. Castor oil and turpentine is a good purge: where the malady depends upon costiveness, purges of aloes should be administered in connexion with warm enemata, stimulating frictions along the spine, and hot baths. Croton oil dropped on the tongue will also be of great benefit: if there should be effusion or compression from fracture of the bones of the cranium, nothing but trephining will be of any service, as we can hardly hope for the absorption of the matter, and the removal of the spicula of bone can alone afford relief to the patient. Paralysis arising from poisoning should be treated as described under the head of mineral poisons. Chronic cases of paralysis arising from want of tone of the nerves and spinal marrow, repeated blistering, introduction of the seton along the spine, electricity, &c., have all been tried with some success. Strychnia, from its peculiar effects upon the animal economy, and its almost exclusive direction to the nerves of motion, makes it a medicine particularly applicable to the treatment of this disease. It may be given in all stages of the malady, but is most serviceable after the reduction of inflammatory action, and when we are convinced that the disease depends upon want of tone in the motor muscles. Great care should be had in its administration, as it is a powerful poison in too large doses, to a large dog; commence with a quarter of a grain in pill, three times daily, and gradually increase to a half grain or more if the animal seems to bear it well. But it should be discontinued immediately on the appearance of any constitutional symptoms, such as spasmodic twitchings of the eyelids or muzzle.--L.] PALSY--MANGE