is of frequent occurrence in the dog; it is also occasionally observed in the horse and the ox. It sometimes appears as an epizootic. It is generally announced by anxiety, agitation, trembling of the hinder limbs, frequent attempts to urine, vain efforts to accomplish it, the evacuation small in quantity, sometimes clear and aqueous, and at other times mucous, laden with sediment, thick and bloody, escaping by jets, painfully and with great difficulty, and then suddenly rushing out in great quantity. To this list of symptoms colic may often be added. The animal drinks with avidity, but seldom eats much, unless at the commencement of the complaint. The skin is hard and dry, he looks at his flanks, and his back and flanks are tender when pressed upon. During the latter portion of my connexion with Mr. Blaine, this disease assumed an epidemic character. There was a great drought through almost every part of the country. The disease was characterised by general uneasiness; continual shifting of the posture; a tucked-up appearance; an anxious countenance; a quick and noisy pulse; continued panting; the urine voided in small quantities, sometimes discharged drop by drop, or complete stoppage of it. The belly hot, swelled, and tender to the touch; the dog becoming strangely irritable, and ready to bite even his master. '1st May', 1824.--Two dogs had been making ineffectual attempts to void their urine for nearly two days. The first was a terrier, and the other a Newfoundland. The terrier was bled, placed in a warm bath, and an aloetic ball, with calomel, administered. He was bled a second time in the evening, and a few drops of water were discharged. On the following day, the urine slowly passed involuntarily from him; but when he attempted to void any, his efforts were totally ineffectual. Balls composed of camphor, pulv. uva ursi, tinct. ferri mur., mass purg., and pulv. lini. et gum. arab., were administered morning, noon, and night. On the 5th the urine still passed involuntarily. Cold lotions were employed, and tonic and astringent medicines administered, with castor oil. He gradually got well, and no trace of the disease remained until June the 6th, when he again became thin and weak, and discharged much bloody urine, but apparently without pain. The uva ursi, oak bark, and powdered gum-arabic were employed. On the 12th he had become much better, and so continued until the 1st of July, when he again exhibited the same complaint more violently than before. He was exceedingly tender on the loins, and screamed when he was touched. He was bled, returned to his uva ursi and powdered gum, and recovered. I saw him two years afterwards apparently well. The Newfoundland dog exhibited a similar complaint, with nearly the same accompaniments. 'May' 1.--He was disinclined to move; his belly was hard and hot, and he was supposed to be costive. Gave an aloetic ball with iron.