At times blood mingles with the urine, with or without coagulation. The cause and the source of it may or may not be determined. Generally speaking it is the result of some strain or blow. A terrier bitch, in January, 1820, had incontinence of urine. No swelling or injury could be detected. I used with her the simple tonic balls. 10th January'.--She is now considerably better, and only a few drops are observed. 2d February'.--The disease which had seemingly been conquered began again to reappear; the medicine had been neglected. Again have recourse to it. 4'th March'.--The disease now appears to be quite checked by the cold lotion and the balls. A CASE OF RUPTURE OF THE BLADDER This is a singular account, and stands almost alone. The patient was a valuable spaniel belonging to that breed known as "The Duke of Norfolk's," and now possessed in its full perfection by the Earl of Albemarle. Professor Simonds shall give his own account: I was informed that almost from a puppy to the time when he was two years old, the dog had always been delicate in his appearance, and was observed to void his urine with difficulty; but there were not sufficient indications of disease for the owner to suppose that medical attendance was necessary until within a few days of his death, and then, finding that the act of staling was effected with increased difficulty, and accompanied with extreme pain; that the dog refused his food, was feverish; that at length there were frequent or ineffective efforts to expel the urine, the dog crying out from extremity of pain, and it was sufficiently evident that great mischief was going on, he was placed under my care; and even then he was walked a mile and a half to my infirmary. My attention was immediately directed to him; the man who brought him informing me that he seemed much easier since he left home. On examination, I at once pronounced that he could not recover; in fact, that he was rapidly sinking; but, from his then state, I could give no opinion with regard to the precise nature or extent of his disease. He was placed upon a bed in an appropriate apartment, with directions not to be disturbed, and in a few hours he died.