The report states, that since the law took effect, July 1848, over 90,000 lbs. of drugs of various kinds have been rejected and condemned in the ports of the United States. Of these, 34,000 lbs. was included under the comprehensive title of Peruvian bark, 16,343 lbs. rhubarb root, 11,707 lbs. jalap root, about 2000 lbs. senna, and about 15,000 lbs. of other drugs. The agitation of the bill which preceded the passage of the law had its effect abroad, and the supply of adulterated drugs from foreign markets has greatly decreased. The domestic supply, has on the contrary increased. Within a recent period, quinine in considerable quantities has been found in the market, adulterated to the extent of some twenty or twenty-five per cent. These frauds were undoubtedly perpetrated by or among our own people. The material used for the adulteration of the quinine was found, on analysis, to be _mannite and sulphate of barites_, in nearly equal weights. The latter article has long been used for this purpose, but not until lately has _mannite_ been detected in the sulphate of quinine. It seems to have been ingeniously substituted for salicine, and a somewhat similar substance prepared from the poplar bark; which articles have heretofore been extensively used for like purposes. The ingenuity consists in the fact, that it is much more difficult to detect the adulterations when effected by the admixture of _mannite_, than when by the admixture of salicine, &c., while the former can be furnished for less than one-fourth of the expense of the latter. For some years past an extensive chemical establishment has been in operation at Brussels, in Belgium, built up at great expense and care, and expressly designed for the manufacture, on a large scale, of imitations of all the most important foreign chemical preparations used in medicine; while, at the same time, an agent was travelling in this country making sales, and soliciting orders in all the principal towns on our sea-board. The articles were prepared and put up with consummate skill and neatness; and the imitation was so perfect that it was impossible for the unsuspecting purchaser to distinguish them from the genuine, notwithstanding that, in some instances, they did not contain over five per cent. of the substances represented by the label. Since the law went into effect at the port of New York, not a single package has been presented for entry. Dr Bailey states, however, that he has been informed that the persons formerly connected with the Brussels firm, are now in this country engaged in the same iniquitous business; hence the adulterations spoken of.--_Annual of Scientific Discovery_, p. 188.