Several so-called detoxicated substitutes for morphine, like "tocanalgine" and "analgine," have been tried; but these turned out to be morphine, and to be equal in strength to morphine as we ordinarily have it. These were the drugs that were advocated in the _Cosmopolitan Magazine_ as "having nothing to do with the morphine-scopolamine treatment originating some years ago in Freiburg." They are morphine treacherously disguised, and the assertions in the _Cosmopolitan_ were never retracted when attention was called to the untruth by the _Journal of the American Medical Association_. In the _American Journal of Obstetrics_ for May, 1915, is a full description of these drugs (page 772). Dr. Joseph Baer reported[213] sixty cases of the morphine-scopolamine treatment at the Michael Reese Maternity Hospital in Chicago, and his results were diametrically opposed to those Dr. Polak himself obtains. The rooms used were large, and had cork-lined sound-proof walls and doors; obstetricians and specially trained nurses were present day and night. The circumstances, then, were the best that could be had. [213] _Jour. Amer. Med. Assoc._, May 22, 1915, lxiv, 21, p. 1723. He used Merck's scopolamine at first, and later a solution made up after the formula of Straub of Freiburg, which is more stable. His doses of morphine were from one-eighth to one-fourth of a grain; Gauss uses one-eighth to one-sixth of a grain; Polak, as much as three-fourths of a grain of narcophin for his first dose. Baer's series ended on February 5, 1915, and of his sixty cases only five were successful. Three of the successful cases received one-fiftieth of a grain of scopolamine in all, and some of the unsuccessful cases got as high as one-sixteenth of a grain, with only wild delirium as a result. The labor was lengthened by about seven hours over untreated cases. As to the amnesia, in twenty-six cases the memory was not dulled at all, although they received more scopolamine than thirty-nine cases in which the memory was cloudy. Thirty-two women had unbearable thirst throughout the labor, and nothing would slake this thirst. Their incessant cries for water were very distressing to the attendants. Headache was present in twenty-seven cases and vertigo in thirty-one, and the headache, which was very intense in some women, lasted for several days after delivery. Pain was diminished in thirty-nine cases, absent in one, as severe as in the average untreated woman in nineteen, and increased in one. That is, only one woman in sixty did not suffer the pain for which the treatment was devised. The reason evidently is that his dose of morphine was too small, yet if he went above this dose he ran the risk of post-partum hemorrhage and of narcotizing the baby. As it was, he had seven post-partum hemorrhages, but in a series of sixty unselected normal delivery cases he had only one hemorrhage.