In the great city his practice as a physician seems to have been from the outset successful, and his knowledge and ability procured him various valuable appointments. He was made a Fellow of The College of Physicians in 1607. This Royal College of Physicians was given a grant of incorporation by Henry VIII in 1518, at the intercession of Chambers, Linacre and Ferdinand Victoria, the King's Physicians, it being under the patronage of Cardinal Wolsey. The first meetings were held at Linacre's house which he bequeathed to the corporation at his death. Until this College was founded practitioners of medicine were licensed to practise by the Bishop of London or by the Dean of St. Paul's. A few years later Harvey was appointed Physician-Extraordinary to King James I, and later yet, after the publication of his great treatise and its dedication to the King, he was made Physician-in-Ordinary to Charles I, whom he attended during the Civil Wars. It must have been about 1615 when Harvey first began expounding his views on the circulation of the blood, during lectures which were delivered at The College of Physicians, but it was not until thirteen years later, i. e., in 1628, that his great work DE MOTU CORDIS was published in Latin, as was customary among scholars, and at Frankfort-on-the-Main, since that was then the great center of the book publishing trade. The treatise was dedicated to King Charles I, in a manner which to us would seem servile, and yet which was according to a custom followed by nearly all of the scholars of the day, who desired to attract not only the attention of royalty, but, in most instances, their benevolent assistance. It is worth while to quote at this point the first sentence or two of his dedication: "To the Most Serene and Invincible CHARLES, of Great Britain, France and Ireland, KING: DEFENDER of the FAITH, Most Serene King, "The heart of animals is the basis of their life, the principle of the whole, the Sun of their Microcosm, that upon which all movement depends, from which all strength proceeds. The King in like manner is the basis of his Kingdom, the Sun of his World, the heart of the Commonwealth, whence all power derives, all grace appears. What I have here written of the movements of the heart I am the more emboldened to present to your Majesty, according to the Custom of the present age, because nearly all things human are done after human examples and many things in the King are after the pattern of the heart."