Finally, a complete fibrous envelope, the fibrous capsule of the eye-ball, is formed about the secondary optic vesicle and its stem (the secondary optic nerve). It originates from the part of the head-plates which immediately encloses the eye. This fibrous envelope takes the form of a closed round vesicle, surrounding the whole of the ball and pushing between the lens and the horny plate at its outer side. The round wall of the capsule soon divides into two different membranes by surface-cleavage. The inner membrane becomes the choroid or vascular coat, and in front the ciliary corona and iris. The outer membrane is converted into the white protective or sclerotic coat--in front, the transparent cornea. The eye is now formed in all its essential parts. The further development--the complicated differentiation and composition of the various parts--is a matter of detail. (FIGURE 2.318. Eye of the chick embryo in longitudinal section (1. from an embryo sixty-five hours old; 2. from a somewhat older embryo; 3. from an embryo four days old). h horny plate, o lens-pit, l lens (in 1. still part of the epidermis, in 2. and 3. separated from it), x thickening of the horny plate at the point where the lens has severed itself, gl corpus vitreum, r retina, u pigment membrane. (From Remak.)) The chief point in this remarkable evolution of the eye is the circumstance that the optic nerve, the retina, and the pigment membrane originate really from a part of the brain--an outgrowth of the intermediate brain--while the lens, the chief refractive body, develops from the outer skin. From the skin--the horny plate--also arises the delicate conjunctiva, which afterwards covers the outer surface of the eyeball. The lachrymal glands are ramified growths from the conjunctiva (Figure 2.286). All these important parts of the eye are products of the outer germinal layer. The remaining parts--the corpus vitreum (with the vascular capsule of the lens), the choroid (with the iris), and the sclerotic (with the cornea)--are formed from the middle germinal layer. The outer protection of the eye, the eye-lids, are merely folds of the skin, which are formed in the third month of human embryonic life. In the fourth month the upper eye-lid reaches the lower, and the eye remains covered with them until birth. As a rule, they open wide shortly before birth (sometimes only after birth). Our craniote ancestors had a third eye-lid, the nictitating membrane, which was drawn over the eye from its inner angle. It is still found in many of the Selachii and Amniotes. In the apes and man it has degenerated, and there is now only a small relic of it at the inner corner of the eye, the semi-lunar fold, a useless rudimentary organ (Chapter 1.5). The apes and man have also lost the Harderian gland that opened under the nictitating membrane; we find this in the rest of the mammals, and the birds, reptiles, and amphibia.