Many in sad faith sought for her, Many with crossed hands sighed for her; But these, our brothers, fought for her, At life's dear peril wrought for her, So loved her that they died for her. Fortunately, the commander-in-chief at the time in Cuba was General Leonard Wood, who had been an army surgeon, and he was the first to appreciate the importance of the discovery. The sanitation of Havana was placed in the hands of Dr. Gorgas, and within nine months the city was cleared of yellow fever, and, with the exception of a slight outbreak after the withdrawal of the American troops, has since remained free from a disease which had been its scourge for centuries. As General Wood remarked, "Reed's discovery has resulted in the saving of more lives annually than were lost in the Cuban War, and saves the commercial interest of the world a greater financial loss each year than the cost of the Cuban War. He came to Cuba at a time when one third of the officers of my staff died of yellow fever, and we were discouraged at the failure of our efforts to control it." Following the example of Havana other centres were attacked, at Vera Cruz and in Brazil, with the same success, and it is safe to say that now, thanks to the researches of Reed and his colleagues, with proper measures, no country need fear a paralyzing outbreak of this once dreaded disease. The scientific researches in the last two decades of the nineteenth century made possible the completion of the Panama Canal. The narrow isthmus separating the two great oceans and joining the two great continents, has borne for four centuries an evil repute as the White Man's Grave. Silent upon a peak of Darien, stout Cortez with eagle eye had gazed on the Pacific. As early as 1520, Saavedra proposed to cut a canal through the Isthmus. There the first city was founded by the conquerors of the new world, which still bears the name of Panama. Spaniards, English and French fought along its coasts; to it the founder of the Bank of England took his ill-fated colony; Raleigh, Drake, Morgan the buccaneer, and scores of adventurers seeking gold, found in fever an enemy stronger than the Spaniard. For years the plague-stricken Isthmus was abandoned to the negroes and the half-breeds, until in 1849, stimulated by the gold fever of California, a railway was begun by the American engineers, Totten and Trautwine, and completed in 1855, a railway every tie of which cost the life of a man. The dream of navigators and practical engineers was taken in hand by Ferdinand de Lesseps in January, 1881. The story of the French Canal Company is a tragedy unparalleled in the history of finance, and, one may add, in the ravages of tropical disease. Yellow fever, malaria, dysentery, typhus, carried off in nine years nearly twenty thousand employees. The mortality frequently rose above 100, sometimes to 130, 140 and in September, 1885, it reached the appalling figure of 176.97 per thousand work people.