When we try to conceive how experiences and their consequences can be entailed, how new acquirements of the 'personal part can have representative effects on the germinal part,' we find ourselves confronted with almost, if not entirely, insuperable difficulties. How could it happen that the constant exercise of memory throughout a lifetime, as, for instance, in the case of an actor, could influence the germ-cells in such a way that in the offspring the same brain-cells which preside over memory will likewise be more highly developed--that is, capable of greater functional activity? We know what Zehnder's answer to such a question would be; he would make the blood the intermediary between the brain-cells and the germ-cells, but we have seen that specific food-stuffs for each specific cell-group cannot be assumed, and that, even if they could, they would not meet the necessities of the case. Yet every one who does not regard the germ-plasm as composed of determinants is constrained to make some such assumption. But if we take our stand upon the theory of determinants, it would be necessary to a transmission of acquired strength of memory that the states of these brain-cells should be communicated by the telegraphic path of the nerve-cells to the germ-cells, and should there modify only the determinants of the brain-cells, and should do so in such a way that, in the subsequent development of an embryo from the germ-cell, the corresponding brain-cells should turn out to be capable of increased functional activity. But as the determinants are not miniature brain-cells, but only groups of biophors of unknown constitution, and are assuredly different from those cells; as they are not 'seed-grains' of the brain-cells, but only living germ-units which, in co-operation with the rest exercise a decisive influence on the memory-cells of the brain, I can only compare the assumption of the transmission of the results of memory-exercise to the telegraphing of a poem, which is handed in in German, but at the place of arrival appears on the paper translated into Chinese.